Investigational Preventative HIV Vaccine Well-Tolerated, Elicited Antibody Responses in Early Clinical Trials

Beth Israel Deaconess Medical Center Press Release

Mosaic-based vaccine includes characteristics from several common strains of HIV.

In the APPROACH multi-site, randomized and controlled study of 393 healthy people in five countries, investigational vaccines were well-tolerated and elicited antibody responses in 100 percent of volunteers.

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U.S. Senator Ed Markey Visits CVVR

Senator Markey speaks with Dr. Dan Barouch about the research being done at the Center for Virology and Vaccine Research.

Senator Markey speaks with Dr. Dan Barouch about the research being done at the Center for Virology and Vaccine Research.

Principal Investigator and Assistant Professor of Medicine, Dr. Kathryn Stephenson discusses the work being done in the lab.

Principal Investigator and Assistant Professor of Medicine, Dr. Kathryn Stephenson discusses the work being done in the lab.

Dr. Dan Barouch and Senator Markey speak to other doctors and researchers in the Center about the importance of Zika research.

Dr. Dan Barouch and Senator Markey speak to other doctors and researchers in the Center about the importance of Zika research.

The lab team with Senator Markey, a proponent of government-funded Zika research.

The lab team with Senator Markey, a proponent of government-funded Zika research.

The Boston Red Sox Celebrate the Center for Virology and Vaccine Research

As the official hospital of the Boston Red Sox, Beth Israel Deaconess Medical Center not only has First Aid Stations set up at Fenway Park, but also has a strong working relationship with it's physicians.  As part of the Red Sox and BIDMC partnership, the Red Sox organization chooses an outstanding physician or researcher to celebrate in a pre-game ceremony at every Friday home game.  On July 8th, Dr. Dan Barouch from the Center for Virology and Vaccine Research was chosen as a BIDMC All Star in honor of his leadership in HIV research.

 

A Red Sox official introduces Dr. Dan Barouch, being honored for his leadership in HIV research.

A Red Sox official introduces Dr. Dan Barouch, being honored for his leadership in HIV research.

Dr. Barouch being given an honorary Red Sox jersey while being recognized as a Medical All-Star.

Dr. Barouch being given an honorary Red Sox jersey while being recognized as a Medical All-Star.

Dr. Barouch and a Red Sox official pose with Wally for a photo opp after being honored as a Medical All-Star.

Dr. Barouch and a Red Sox official pose with Wally for a photo opp after being honored as a Medical All-Star.

Boston-Based Research Shows Promise for Zika Virus Vaccine

  • WGHB News
  • By:  Marilyn Schairer & Michael Agnello

Researchers at Boston's Beth Israel  Deaconess Medical Center have made some promising advances in developing a vaccine to halt the spread of the mosquito-born Zika virus.

Less than a year after Brazilian officials confirmed the country’s first case in 2015, the World Health Organization declared the virus a public health emergency due to its link to fetal microcephaly. Since then, health officials have made stopping the spread of the Zika virus  a global priority.

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Zika Update: Two New Zika Vaccine Effective in Mouse Models

  • Nature World News
  • By Jean Raphael

Two new vaccines against Zika virus have proven its effectiveness in preclinical trials involving mice challenged with Zika virus, suggesting that Zika vaccines for humans are still achievable.

Their findings, published in the journal Nature, showed that the two experimental vaccines have protected mice from ZIka virus four to eight weeks after receiving the initial injections.

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New Studies Show Just How Tricky the Zika Virus Is

  • NBC News
  • by MAGGIE FOX

A batch of new studies show the Zika virus is trickier than it appeared at first glance, lurking for months in pregnant females and interfering with the immune system's response.

The findings help explain why the virus seems so mild in some people, yet causes devastating birth defects. And while the data suggests it is not going to be so easy to fight the epidemic, at least two studies offer some hope for a good, protective vaccine.

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How An Electric Shock Could One Day Protect You From Zika

This summer, it's not just athletes who are looking to set world records. Scientists are also trying to break a record — for how quickly they can make a vaccine for a new virus.

It's for Zika. And one team is leading the pack.

The biotech company Inovio just got the first approval from the Food and Drug Administration to test an experimental vaccine in people. They've already shown the virus protects monkeys from Zika, says the company's president, Joseph Kim. And a small study begins in people in a few weeks.

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2 Types of Vaccines Protect Against Zika Virus in Mice: Interview

  • WBUR
  • By Jonathan Cain

"We hope that this news will electrify and galvanize the vaccine effort against Zika virus," says Dr. Dan Barouch of Beth Israel Deaconess Medical Center and Harvard Medical School.

Barouch is senior author of a paper just out in the journal Nature reporting some promising findings on potential Zika vaccines — at least, in mice. Researchers found that two different types of vaccines — one using DNA and one using an inactivated form of the virus — seemed to confer complete protection against the virus that has been declared a public health emergency through much of the Americas.

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Breakthrough Zika Vaccine Under Development by Boston Researchers

  • The Boston Herald
  • Lindsay Kalter

A group of researchers at Beth Israel Deaconess Medical Center are testing a vaccine for the Zika virus they say has exceeded expectations in animal trials, requiring only one shot to effectively stave off the disease that has been linked to devastating birth defects.

“The protection was striking,” said lead researcher Daniel Barouch, director of the Center for Virology and Vaccine Research at Beth Israel. “This gives us an option for a safe and effective vaccine for humans.”

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