CVVR Clinical Trials Unit

The focus of the CVVR Clinical Trials Unit is early phase and first-in-human studies of novel preventive and therapeutic approaches to viral illnesses and other infections. This page provides helpful references via links provided by AVAC: Global Advocacy for HIV Prevention, the National Institutes of Health HIV Vaccine and Prevention Trials Networks, and other organizations. 

Contact Information: 

T: 617 735 4610


Want to Participate?


PGT121 and VRC07-523LS Antibody Trial (T003)

HIV Vaccine Trial (HTX1002)

CVVR Volunteer Registry

Want to read more on Zika and HIV?

Click Here→

Our Team:


Jessica Ansel, Clinical Research Nurse Coordinator

Jess is a Registered Nurse originally from New York.  She received her BA in Chemistry from SUNY Geneseo in 2010 and her BS in Nursing from Stony Brook University in 2014.  Jess began her nursing career at Good Samaritan Hospital in West Islip, NY, where she gained experience working on a fast-paced medical surgical unit.  In 2015, she moved to Boston and took a position within the CVVR as a Clinical Research Nurse Coordinator.  She quickly developed a passion for research and the CVVR’s mission.  Jess is currently enrolled in the Adult Geriatric Nurse Practitioner program at U Mass Boston and plans to use this degree to further her health care and research efforts.  In her spare time, she enjoys cooking, baking, and attending Orange Theory fitness classes.

Diane Ananos, Clinical Research Nurse Coordinator

Diane comes from a line of nurses that stretches back two generations. She received her BS in nursing from Penn State University in 2006. She began her career at Mount Sinai Hospital in Manhattan, working in the pediatric intensive care unit for 4 years, followed by 2 years in the medicine / pediatric outpatient clinic. In 2012 she took a position as a research coordinator in the Division of Pediatric Allergy and Immunology where she gained experience in the design and execution of clinical trials.  Continuing to follow her passion for research, in 2016 she moved to Boston where she joined the CVVR CTU as a clinical research coordinator working on HIV vaccine / immunotherapeutic and Zika vaccine trials.  She plans to obtain a graduate degree as a Family Nurse Practitioner and to one day lead her own research studies. In her spare time, Diane enjoys visiting local museums, drawing and cheering on the Patriots.

Kate Jaegle, Clinical Research Nurse Coordinator

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Kate is one of the clinical research nurse coordinators and started in February 2018.  She graduated from University of Connecticut in 2012 with a BSN.  During her time at UCONN she studied abroad in Cape Town, South Africa and worked with the HIV/AIDS population.  From there, she has worked as a staff nurse both in Connecticut and in Boston at Spaulding Hospital in Cambridge and New England Baptist Hospital.  She is currently pursuing a Master’s Degree in Nursing specializing in the Adult-Gerontologic population.

Connor Bradshaw, Clinical Research Assistant II

Connor received his B.S. in Biology with a concentration in Health Sciences from Emmanuel College in 2017. During this time, he was a member of the Men’s Soccer Team, served on the Academic Integrity Board, and participated in Emmanuel College’s Alternative Spring Break, where he and other students volunteered their time at various service locations throughout the Boston area. As an undergraduate, he conducted clinical research at Boston Medical Center that looked to prove a method of quantifying fibrotic tissue build-up as a result of radiation therapy in head and neck cancer patients, and to hopefully improve treatment options and quality of life outcomes for future patients in the field. In his spare time, he enjoys exercising, reading, and exploring new parts of Boston. Connor is passionate about public health and infectious disease research, and hopes to go on to graduate school to learn how to better address the health care inequities that exist in the world.

Anna Tyler, Clinical Research Assistant II

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Anna graduated from Trinity College in 2017 with a Bachelor of Science in biology with a concentration in biomedical sciences. At Trinity, she worked as a biology laboratory teaching assistant and has previously conducted research on Vibrio cholerae vaccines at Massachusetts General Hospital. Anna has long been interested in infectious diseases and is currently deciding between pursuing an M.P.H. in epidemiology or an M.D. to become an infectious disease specialist. One would most likely find Anna either at the beach, listening to any and all types of music, or attempting not to spill food on herself.

Tatenda Makoni, Clinical Research Assistant II

Tatenda graduated from Gordon College with a Bachelor's of Science degree in Chemistry - Biochemistry and Health Professions concentrations in December 2017. Her last summer as an undergraduate was spent at the Nelson Mandela School of Medicine in KwaZulu - Natal, South Africa where she performed question based HIV research under the mentorship of Dr. Zaza Ndhlovu. Tatenda hopes to pursue a career in medicine, public health, and HIV research. She eventually plans on going back to her home country of Zimbabwe where she hopes to positively influence the policy making in the government health sector. During her spare time, Tatenda enjoys watching TV, going to the beach and trying out different coffee shops.

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