Stephanie Jost

Stephanie Jost, Ph.D.

Stephanie Jost, Ph.D.

Principal Investigator
Jost Laboratory

Assistant Professor of Medicine, Harvard Medical School

sjost@bidmc.harvard.edu
T: 617-735-4615
F: 617-735-4527

Education

  • 2000, University of Geneva, Switzerland, B.Sc. (Biology)
  • 2002, University of Geneva, Switzerland, M.Sc. (Virology)
  • 2007, Swiss Federal Institute of Technology Lausanne (EPFL), Switzerland, Ph.D. (Virology)

Training

  • 2008-2013, Postdoctoral Research Fellow, Ragon Institute of MGH, MIT and Harvard, Boston, MA

Appointments

  • 2013-2015, Director of the Ragon Institute Human Immune Monitoring Core, Boston, MA
  • 2013-2016, Assistant in Immunology, Massachusetts General Hospital, Boston, MA
  • 2013-2017, Instructor in Medicine, Harvard Medical School, Boston, MA
  • 2016-Present, Staff Ph.D., Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA
  • 2017-Present, Assistant Professor of Medicine, Harvard Medical School

Honors

  • 1996, Givaudan-Roure Award in physics and chemistry
  • 2003, Prix Arditi (Swiss Arditi Foundation) for Outstanding Master’s Thesis in Biology
  • 2008, Prospective Researcher Fellowship, Swiss National Science Foundation
  • 2009, Keystone Symposia Scholarship, HIV-1 immunobiology: from infection to immune control, Keystone, Colorado
  • 2009, MGH ECOR Fund for Medical Discovery Award
  • 2010, Keystone Symposia Scholarship, HIV Vaccines and Viral Immunity, Banff, Alberta, Canada
  • 2012, AIDS Vaccine 2012 Conference Scholarship, Boston, MA
  • 2012, Harvard University Center for AIDS Research Scholar Award

Publications

  • Tan CS., Ghofrani J., Geiger E., Koralnik IJ, Jost S., Decreased JC virus-specific antibody-dependent cellular cytotoxicity in HIV-seropositive PML survivors. JAIDS; 2019 (In Press)

  • DeWolfe D, Aid M, McGann K, Ghofrani J, Geiger E, Helzer C, Malik S, Kleiboeker S, Jost S, Tan CS. NK Cells Contribute to the Immune Risk Profile in Kidney Transplant Candidates. (2019) Frontiers in Immunology. 10:1890. [Article]

  • Ghofrani J, Lucar O, Dugan H, Reeves RK, Jost S. Semaphorin 7A modulates cytokine-induced memory-like responses by human natural killer cells. (2019) European Journal of Immunology. 49(8):1153-1166.

  • Hogan LE, Hanhauser E, Hobbs KS, Palmer CD, Robles Y, Jost S, LaCasce AS, Abramson J, Hamdan A, Marty FM, Kuritzkes DR, Henrich TJ. Human Herpes Virus 8 in HIV-1 infected individuals receiving cancer chemotherapy and stem cell transplantation. (2018) PLoS One. 13(5):e0197298. [Article]

  • Hogan LE, Körner C, Hobbs K, Simoneau CR, Thanh C, Gibson EA, Palmer CD, Pandit A, Marty FM, Kuritzkes DR, Jost S, Ritz J, Henrich TJ. NK-cell activation is associated with increased HIV transcriptional activity following allogeneic hematopoietic cell transplantation. (2018) Blood Advances. 2(12):1412-1416. [Article]

  • Manickam C, Nwanze C, Ram DR, Shah SV, Smith S, Jones R, Hueber B, Kroll K, Varner V, Goepfert P, Jost S, Reeves RK. Progressive lentivirus infection induces natural killer cell receptor-expressing B cells in the gastrointestinal tract. (2018) AIDS. 32(12):1571-1578. [Article]

  • Körner C, Simoneau CR, Schommers P, Granoff M, Ziegler M, Hölzemer A, Lunemann S, Chukwukelu J, Corleis B, Naranbhai V, Kwon DS, Scully EP, Jost S, Kirchhoff F, Carrington M, Altfeld M. HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells. (2017) Cell Host & Microbe. 22(1):111-119.e4.

  • Henrich TJ, Hobbs KS, Hanhauser E, Scully E, Hogan LE, Robles YP, Leadabrand KS, Marty FM, Palmer CD, Jost S, Korner C, Li JZ, Ghandi RT, Hamdan A, Abramson J, LaCasce AS, Kuritzkes DR. Human Immunodeficiency Virus Type 1 Persistence Following Systemic Chemotherapy for Malignancy. (2017) The Journal of infectious diseases. 216(2):254-262. [Article]

  • Henrich TJ, Hanhauser E, Harrison LJ, Palmer CD, Romero-Tejeda M, Jost S, Bosch RJ, Kuritzkes DR. CCR5-Delta32 Heterozygosity, HIV-1 Reservoir Size, and Lymphocyte Activation in Individuals Receiving Long-term Suppressive Antiretroviral Therapy. (2016) The Journal of infectious diseases.213(5):766-70. [Article]

  • Palmer CD, Romero-Tejeda M, Scully EP, Lockhart A, Seaman MS, Goldenthal A, Piechocka- Trocha A, Walker B, Chibnik LB, Jost S, Porichis F. Increased frequencies of CD8+CD57+ T cells are associated with antibody neutralization breadth against HIV in viraemic controllers. (2016) Journal of the International AIDS Society. 19(1):21136