Chen Tan

C. Sabrina Tan, M.D.

C. Sabrina Tan, M.D.

Principal Investigator and CTU Principal Investigator
Tan Laboratory

Assistant Professor of Medicine, Harvard Medical School; Staff Physician, Division of Infectious Diseases, Beth Israel Deaconess Medical Center

ctan@bidmc.harvard.edu
T: 617-632-7706
F: 617-632-7626

Education

  • Massachusetts Institute of Technology, S.B., 1997 (Chemistry)
  • New York University School of Medicine, M.D., 2002

Training

  • 2002-2005, Intern and Resident in Medicine, New York University/Bellevue Hospital, New York, NY
  • 2005-2008, Fellow in Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA

Appointments

  • 2008-2010, Instructor in Medicine, Harvard Medical School, Boston, MA
  • 2010-Present, Assistant Professor of Medicine, Harvard Medical School, Boston, MA
  • 2008-Present, Staff Physician, Beth Israel Deaconess Medical Center, Boston, MA

Honors

  • 1993, Westinghouse Science Talent Search, semi-finalist
  • 1992, The American Ceramic Society Certificate of Excellence
  • 2002, NYU School of Medicine Honors Degree in Physiology and Neuroscience
  • 2007, ICAAC ID Fellows’ Grant Program
  • 2008, Young Investigator Award for CROI 2008, Boston, MA
  • 2008, Max Finland Award for Excellence in Research

Publications

  • Satyanarayana G, Hammond SP, Broge TA Jr, Mackenzie MR, Viscidi R, Politikos I, Koralnik IJ, Cutler CS, Ballen K, Boussiotis V, Marty FM, Tan CS. BK polyomavirus reactivation after reduced-intensity double umbilical cord blood cell transplantation. Transpl Immunol. 2015 Mar;32(2):116-20. doi: 10.1016/j.trim.2014.12.002. Epub 2014 Dec 20. PubMed PMID: 25536223; PubMed Central PMCID: PMC4368450. [Article]

  • Stephenson KE, Wegmann F, Tomaka F, et al. Comparison of shortened mosaic HIV-1 vaccine schedules: a randomised, double-blind, placebo-controlled phase 1 trial (IPCAVD010/HPX1002) and a preclinical study in rhesus monkeys (NHP 17-22) [published online ahead of print, 2020 Feb 17] [published correction appears in Lancet HIV. 2020 Feb 28;:]. Lancet HIV. 2020;S2352-3018(20)30001-1. doi:10.1016/S2352-3018(20)30001-1 [Article]

  • Khoury MN, Tan CS, Peaslee M, Koralnik IJ. CSF viral escape in a patient with HIV-associated neurocognitive disorder. J Neurovirol. 2013 Aug;19(4):402-5. doi: 10.1007/s13365-013-0175-9. Epub 2013 Jun 5. PubMed PMID: 23737348; PubMed Central PMCID: PMC3759614. [Article]

  • Chalkias S, Mackenzie MR, Gay C, Dooley C, Marty FM, Moss RB, Li T, Routh RL, Walsh SR, Tan CS. DAS181 treatment of hematopoietic stem cell transplant patients with parainfluenza virus lung disease requiring mechanical ventilation. Transpl Infect Dis. 2014 Feb;16(1):141-4. doi: 10.1111/tid.12177. Epub 2014 Jan 3. PubMed PMID: 24383501; PubMed Central PMCID: PMC4469988. [Article]

  • Tan CS., Ghofrani J., Geiger E., Koralnik IJ, Jost S., Decreased JC virus-specific antibody-dependent cellular cytotoxicity in HIV-seropositive PML survivors. JAIDS; 2019 (In Press)

  • Tan CS, Broge TA Jr, Seung E, Vrbanac V, Viscidi R, Gordon J, Tager AM, Koralnik IJ. Detection of JC virus-specific immune responses in a novel humanized mouse model. PLoS One. 2013;8(5):e64313. doi: 10.1371/journal.pone.0064313. Print 2013. PubMed PMID: 23700470; PubMed Central PMCID: PMC3658964. [Article]

  • Tan CS, Broge TA Jr, Ngo L, Gheuens S, Viscidi R, Bord E, Rosenblatt J, Wong M, Avigan D, Koralnik IJ. Immune reconstitution after allogeneic hematopoietic stem cell transplantation is associated with selective control of JC virus reactivation. Biol Blood Marrow Transplant. 2014 Jul;20(7):992-9. doi: 10.1016/j.bbmt.2014.03.018. Epub 2014 Mar 27. PubMed PMID: 24680976; PubMed Central PMCID: PMC4057943. [Article]

  • Gabardi S, Ramasamy S, Kim M, Klasek R, Carter D, Mackenzie MR, Chandraker A, Tan CS. Impact of HMG-CoA reductase inhibitors on the incidence of polyomavirus-associated nephropathy in renal transplant recipients with human BK polyomavirus viremia. Transpl Infect Dis. 2015 Aug;17(4):536-43. doi: 10.1111/tid.12402. Epub 2015 Jun 26. PubMed PMID: 25989423; PubMed Central PMCID: PMC4529764. [Article]

  • Tan CS, Bord E, Broge TA Jr, Glotzbecker B, Mills H, Gheuens S, Rosenblatt J, Avigan D, Koralnik IJ. Increased program cell death-1 expression on T lymphocytes of patients with progressive multifocal leukoencephalopathy. J Acquir Immune Defic Syndr. 2012 Jul 1;60(3):244-8. doi: 10.1097/QAI.0b013e31825a313c. PubMed PMID: 22549384; PubMed Central PMCID: PMC3400136. [Article]

  • DeWolfe D, Aid M, McGann K, Ghofrani J, Geiger E, Helzer C, Malik S, Kleiboeker S, Jost S, Tan CS. NK Cells Contribute to the Immune Risk Profile in Kidney Transplant Candidates. (2019) Frontiers in Immunology. 10:1890. [Article]