Chen Tan

C. Sabrina Tan, M.D.

C. Sabrina Tan, M.D.

Principal Investigator
Tan Laboratory

Assistant Professor of Medicine, Harvard Medical School; Staff Physician, Division of Infectious Diseases, Beth Israel Deaconess Medical Center

ctan@bidmc.harvard.edu
T: 617-632-7706
F: 617-632-7626

Education

  • Massachusetts Institute of Technology, S.B., 1997 (Chemistry)
  • New York University School of Medicine, M.D., 2002

Training

  • 2002-2005, Intern and Resident in Medicine, New York University/Bellevue Hospital, New York, NY
  • 2005-2008, Fellow in Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA

Appointments

  • 2008-2010, Instructor in Medicine, Harvard Medical School, Boston, MA
  • 2010-Present, Assistant Professor of Medicine, Harvard Medical School, Boston, MA
  • 2008-Present, Staff Physician, Beth Israel Deaconess Medical Center, Boston, MA

Honors

  • 1993, Westinghouse Science Talent Search, semi-finalist
  • 1992, The American Ceramic Society Certificate of Excellence
  • 2002, NYU School of Medicine Honors Degree in Physiology and Neuroscience
  • 2007, ICAAC ID Fellows’ Grant Program
  • 2008, Young Investigator Award for CROI 2008, Boston, MA
  • 2008, Max Finland Award for Excellence in Research

Publications

  • Stephenson KE, Wegmann F, Tomaka F, et al. Comparison of shortened mosaic HIV-1 vaccine schedules: a randomised, double-blind, placebo-controlled phase 1 trial (IPCAVD010/HPX1002) and a preclinical study in rhesus monkeys (NHP 17-22) [published online ahead of print, 2020 Feb 17] [published correction appears in Lancet HIV. 2020 Feb 28;:]. Lancet HIV. 2020;S2352-3018(20)30001-1. doi:10.1016/S2352-3018(20)30001-1 [Article]

  • Tan CS., Ghofrani J., Geiger E., Koralnik IJ, Jost S., Decreased JC virus-specific antibody-dependent cellular cytotoxicity in HIV-seropositive PML survivors. JAIDS; 2019 (In Press)

  • DeWolfe D, Aid M, McGann K, Ghofrani J, Geiger E, Helzer C, Malik S, Kleiboeker S, Jost S, Tan CS. NK Cells Contribute to the Immune Risk Profile in Kidney Transplant Candidates. (2019) Frontiers in Immunology. 10:1890. [Article]

  • Karantanos T, Kim HT, Tijaro-Ovalle NM, Li L, Cutler C, Antin JH, Ballen K, Marty FM, Tan CS, Ritz J, Politikos I, Boussiotis V. Reactivation of BK virus after double umbilical cord blood transplantation in adults correlates with impaired reconstitution of CD4(+) and CD8(+) T effector memory cells and increase of T regulatory cells. Clin Immunol. 2019 PMID 31255803.

  • Tan CS, Gabardi S, Pavlakis M, Survey of BK virus screening practices by American Society of Transplantation members. Clin Transplant; 2019 (In Press) PMID 31152561

  • Modjarrad K, Lin L, George SL, Stephenson KE, Eckels KH, De La Barrera RA, Jarman RG, Sondergaard E, Tennant J, Ansel JL, Mills K, Koren M, Robb ML, Barrett J, Thompson J, Kosel AE, Dawson P, Hale A, Tan CS, Walsh SR, Meyer KE, Brien J, Crowell TA, Blazevic A, Mosby K, Larocca RA, Abbink P, Boyd M, Bricault CA, Seaman MS, Basil A, Walsh M, Tonwe V, Hoft DF, Thomas SJ, Barouch DH*, Michael NL*. Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials. Lancet 2018; 391:563-571. [Article]

  • DeWolfe D, Gandhi J, Mackenzie MR, Broge TA Jr, Bord E, Babwah A, Mandelbrot DA, Pavlakis M, Cardarelli F, Viscidi R, Chandraker A, Tan CS. Pre-transplant immune factors may be associated with BK polyomavirus reactivation in kidney transplant recipients. PLoS One. 2017;12(5):e0177339. doi: 10.1371/journal.pone.0177339. eCollection 2017. PubMed PMID: 28562595; PubMed Central PMCID: PMC5451008. [Article]

  • Tan CS. Reactivation of Multiple Infectious Pathogens after Hematopoietic Stem Cell Transplantation. Acta Haematol 2017; 138(1): 1-2.

  • Satyanarayana G, Hammond SP, Broge TA Jr, Mackenzie MR, Viscidi R, Politikos I, Koralnik IJ, Cutler CS, Ballen K, Boussiotis V, Marty FM, Tan CS. BK polyomavirus reactivation after reduced-intensity double umbilical cord blood cell transplantation. Transpl Immunol. 2015 Mar;32(2):116-20. doi: 10.1016/j.trim.2014.12.002. Epub 2014 Dec 20. PubMed PMID: 25536223; PubMed Central PMCID: PMC4368450. [Article]

  • Gabardi S, Ramasamy S, Kim M, Klasek R, Carter D, Mackenzie MR, Chandraker A, Tan CS. Impact of HMG-CoA reductase inhibitors on the incidence of polyomavirus-associated nephropathy in renal transplant recipients with human BK polyomavirus viremia. Transpl Infect Dis. 2015 Aug;17(4):536-43. doi: 10.1111/tid.12402. Epub 2015 Jun 26. PubMed PMID: 25989423; PubMed Central PMCID: PMC4529764. [Article]