Whitney Laboratory

Principal Investigator: James B. Whitney, Ph.D.

Dr. James Whitney’s expertise is molecular virology, reservoir dynamics, and pre-clinical development using the SIV-rhesus monkey model. His current research is focused on intra-host virus dynamics, and evolution of SIV as they pertain to viral persistence on potent antiretroviral therapy. Towards this end, he has established primate models to examine both sexual transmission, and SIV persistence on intensified antiretroviral therapy. Dr. Whitney has recently published on the early seeding and genesis of the viral reservoir and discovery of a novel class of safe, orally deliverable and highly potent, viral latency reversing agents (TLR7 agonists). His current work focuses on delineating the nature and maintenance of reservoirs, building and expanding on his prior work.