By: Matthew Disler Harvard Magazine, May 8th, 2017
To understand the outbreak of a disease like Zika, and ultimately to fight it, researchers must work on multiple levels. There are questions of molecules and chemical processes: how does the virus infect a cell, and what components provoke an immune response that can be harnessed for treatments and vaccines? On a larger scale, there are questions about populations. How does a pathogen discovered in Uganda spread from French Polynesia to Brazil and the Caribbean? How do families and individuals cope with infants born with complications from the disease, like microcephaly (an abnormally small head size) and neurological damage, whose lasting effects still have not been fully determined? Harvard researchers have already made strides at all of these levels, and, as North America prepares for another outbreak this summer, now seek to answer further questions.
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A new study has demonstrated that combining an experimental vaccine with an innate immune stimulant may help lead to viral remission in people living with HIV. In animal trials, the combination decreased levels of viral DNA in peripheral blood and lymph nodes, and improved viral suppression and delayed viral rebound following discontinuation of anti-retroviral therapy (ART).
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by Linda Carroll and Samuel Sarmiento, MD NBC Health, August 4th, 2016
The race to develop a safe and effective vaccine against the Zika virus got one step closer Thursday, when a team of researchers reported positive results in the latest round of testing in monkeys.
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WGHB News By: Marilyn Schairer & Michael Agnello Researchers at Boston’s Beth Israel Deaconess Medical Center have made some promising advances in developing a vaccine to halt the spread of […]
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Nature World News By Jean Raphael Two new vaccines against Zika virus have proven its effectiveness in preclinical trials involving mice challenged with Zika virus, suggesting that Zika vaccines for […]
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Studying Zika
/in NewsTo understand the outbreak of a disease like Zika, and ultimately to fight it, researchers must work on multiple levels. There are questions of molecules and chemical processes: how does the virus infect a cell, and what components provoke an immune response that can be harnessed for treatments and vaccines? On a larger scale, there are questions about populations. How does a pathogen discovered in Uganda spread from French Polynesia to Brazil and the Caribbean? How do families and individuals cope with infants born with complications from the disease, like microcephaly (an abnormally small head size) and neurological damage, whose lasting effects still have not been fully determined? Harvard researchers have already made strides at all of these levels, and, as North America prepares for another outbreak this summer, now seek to answer further questions.
New therapeutic vaccine approach holds promise for HIV remission
/in NewsA new study has demonstrated that combining an experimental vaccine with an innate immune stimulant may help lead to viral remission in people living with HIV. In animal trials, the combination decreased levels of viral DNA in peripheral blood and lymph nodes, and improved viral suppression and delayed viral rebound following discontinuation of anti-retroviral therapy (ART).
Beth Israel Is Launching a Zika Vaccine Trial
/in NewsThe trial could start as early as October, doctors say.
The Race for a Zika Vaccine
/in NewsIn the throes of an epidemic, researchers investigate how to inoculate against the disease.
‘Striking’ Results from Early Zika Vaccine Trial
/in NewsThe race to develop a safe and effective vaccine against the Zika virus got one step closer Thursday, when a team of researchers reported positive results in the latest round of testing in monkeys.
U.S. Senator Ed Markey Visits CVVR
/in NewsThe Boston Red Sox Celebrate the Center for Virology and Vaccine Research
/in NewsBoston-Based Research Shows Promise for Zika Virus Vaccine
/in NewsWGHB News By: Marilyn Schairer & Michael Agnello Researchers at Boston’s Beth Israel Deaconess Medical Center have made some promising advances in developing a vaccine to halt the spread of […]
Zika Update: Two New Zika Vaccine Effective in Mouse Models
/in NewsNature World News By Jean Raphael Two new vaccines against Zika virus have proven its effectiveness in preclinical trials involving mice challenged with Zika virus, suggesting that Zika vaccines for […]
Two Zika vaccine candidates shown to completely protect mice from the virus
/in NewsThe vaccines still need to go through human clinical trials.