Keith Reeves

R. Keith Reeves, Ph.D.

R. Keith Reeves, Ph.D.

Principal Investigator
Reeves Laboratory

Associate Professor of Medicine and Director of Harvard CFAR Advanced Technologies Core

rreeves@bidmc.harvard.edu
T: 617-735-4586
F: 508-624-8172

Education

  • MS State University, Starkville, MS, B.S., 2002 (Microbiology)
  • University of Alabama Medical School, Birmingham, AL, Ph.D., 2007 (Virology)

Training

  • 2007-2014, Postdoctoral Research Fellow in Medicine, New England Primate Research Center, Harvard Medical School

Appointments

  • 2011 – 2013, Instructor in Medicine, Harvard Medical School, NEPRC
  • 2013, Instructor in Medicine, Beth Israel Deaconess Medical Center
  • 2013 –  present, Adjunct Assistant Professor, Department of Pathology, Emory University
  • 2014 – present, Assistant Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center

Honors

  • 2000, H. H. Harned Memorial Award/Scholarship for Most Outstanding Undergraduate Student in Microbiology, MSU
  • 2002-2003, E. B. Carmichael Scholar – One chosen annually from all University of Alabama at Birmingham graduate students in biomedical disciplines
  • 2003-2007, NIH Predoctoral Fellowship – Basic Mechanisms in Virology
  • 2006, Raymond N. Hiramoto Award in Microbiology, University of Alabama at Birmingham
  • 2008, Early Career Investigator, OCTAVE Mucosal Immunity and Vaccine Design, Cape Town, South Africa
  • 2008, Young Investigator Award, 26th Annual Nonhuman Primate Models for AIDS Symposium, San Juan, Puerto Rico
  • 2009, Early Stage Investigator Award, CHAVI/HVTN
  • 2009, Young Investigator Award, 16th Annual Conference on Retroviruses and Opportunistic Infections, Montreal, Quebec, CAN
  • 2009, Keystone Symposia Scholarship, Prevention of HIV/AIDS, Keystone, Colorado
  • 2010, Young Investigator Award, 17th Annual Conference on Retroviruses and Opportunistic Infections, San Francisco, CA
  • 2011, Early Stage Investigator Award, CHAVI/HVTN
  • 2011, Conference Scholarship, AIDS Vaccine, Bangkok, Thailand
  • 2012, Early Career Grant, AAI

Publications

  • Aid, M., Ram, D. R., Bosinger, S. E., Barouch, D. H., & Reeves, R. K. (2020). Delineation and Modulation of the Natural Killer Cell Transcriptome in Rhesus Macaques During ZIKV and SIV Infections. Frontiers in Cellular and Infection Microbiology10. doi: 10.3389/fcimb.2020.00194 [Article]

  • Hueber, B., Curtis, A. D., Kroll, K., Varner, V., Jones, R., Pathak, S., … Reeves, R. K. (2020). Functional Perturbation of Mucosal Group 3 Innate Lymphoid and Natural Killer Cells in Simian-Human Immunodeficiency Virus/Simian Immunodeficiency Virus-Infected Infant Rhesus Macaques. Journal of Virology94(5). doi: 10.1128/jvi.01644-19 [Article]

  • Manickam C, Reeves RK. Silent damage? Occult HCV replication and histological disease may occur following apparent HCV clearance. EBioMedicine. 2019;47:12-13. doi:10.1016/j.ebiom.2019.08.029. [Article]

  • Lucar, O., Reeves, R.K., and Jost, S. 2019 A natural impact: NK cells at the intersection of cancer and HIV disease. Front. Immunol. 10:1850. PMID: 31474977. PMCID: PMC6705184

  • Montano, M., Bhasin, S., D’Aquila, R.T., Erlandson, K.M., Evans, W.J., Funderburg, N.T., Justice, A., Ndhlovu, L., Ojikutu, B., Pahor, M., Pahwa, S., Ryan, A.S., Schrack, J., Schultz, M.B., Sebatiani, P, Sinclair, D., Tripp, J., Walker, B., Womack, J.A., Yung, R., and Reeves, R.K. Harvard HIV and aging workshop: Perspective and priorities from Claude D. Pepper Centers and Centers for AIDS Research. AIDS Research and Human Retroviruses Epub. doi: 10.1089/AID.2019.0130. PMID: 31456412 [Article]

  • Truitt, L. L., Yang, D., Espinoza, D. A., Fan, X., Ram, D. R., Moström, M. J., … Wu, C. (2019). Impact of CMV Infection on Natural Killer Cell Clonal Repertoire in CMV-Naïve Rhesus Macaques. Frontiers in immunology, 10, 2381. doi:10.3389/fimmu.2019.02381 [Article]

  • Lewis, G., Ackerman, M.E., Scarlatti, G, Moog, C, Robert-Guroff, M., Kent, S.J., Overbaugh, J., Reeves, R.K., Ferrari, G., and Thyagarajan, B. Knowns and unknowns of assaying antibody-dependent cell-mediated cytotoxicity against HIV-1. 2019. Front. Immunol. 10:1025. PMID: 31134085. PMCID: PMC6522882 [Article]

  • Ram, R., Manickam, C, Lucar, O., Shah, S., and Reeves, R.K. Memory and antigen-specific NK cell responses in HIV/SIV infections: A roadmap to cell-based therapeutics? 2019. J. Leukoc. Bio. 105(6):1253-1259. PMID: 30730588. PMID: 30730588. PMCID: PMC6536345 [Article]

  • Manickam, C., Shah, S., Nohara, J., Ferrari, G., Reeves, R.K. ­­­­2019 Monkeying around: Using nonhuman primate models to study NK cell biology in HIV infections. Front. Immunol. 10:1124. PMID: 31191520. PMCID: PMC6540610. [Article]

  • Manickam, C., Li, H., Kroll, K., and Reeves, R.K. Non-linear multidimensional flow cytometry analyses delineate NK cell phenotypes in normal and HIV-infected chimpanzees. 2019. Int. Immunol. 5;31(3):175-180. PMID: 30418531. PMCID: PMC6400041 [Article]