Publications
2023
Solforosi, L., Costes, L.M.M., Tolboom, J.T.B.M. et al. Booster with Ad26.COV2.S or Omicron-adapted vaccine enhanced immunity and efficacy against SARS-CoV-2 Omicron in macaques. Nat Commun 14, 1944 (2023). https://doi.org/10.1038/s41467-023-37715-2
[Article]
Jacob-Dolan, C., Yu, J., McMahan, K. et al. Immunogenicity and protective efficacy of GBP510/AS03 vaccine against SARS-CoV-2 delta challenge in rhesus macaques. npj Vaccines 8, 23 (2023). https://doi.org/10.1038/s41541-023-00622-0
[Article]
Miller, J., Hachmann, N. P., Collier, A. Y., Lasrado, N., Mazurek, C. R., Patio, R. C., Powers, O., Surve, N., Theiler, J., Korber, B., & Barouch, D. H. (2023). Substantial Neutralization Escape by SARS-CoV-2 Omicron Variants BQ.1.1 and XBB.1. The New England journal of medicine, 10.1056/NEJMc2214314. Advance online publication. https://doi.org/10.1056/NEJMc2214314
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Collier, A. Y., Miller, J., Hachmann, N. P., McMahan, K., Liu, J., Bondzie, E. A., Gallup, L., Rowe, M., Schonberg, E., Thai, S., Barrett, J., Borducchi, E. N., Bouffard, E., Jacob-Dolan, C., Mazurek, C. R., Mutoni, A., Powers, O., Sciacca, M., Surve, N., VanWyk, H., … Barouch, D. H. (2023). Immunogenicity of BA.5 Bivalent mRNA Vaccine Boosters. The New England journal of medicine, 10.1056/NEJMc2213948. Advance online publication. https://doi.org/10.1056/NEJMc2213948
[Article]
2022
Cooper, A., Sidaway, A., Chandrashekar, A., Latta, E., Chakraborty, K., Yu, J., McMahan, K., Giffin, V., Manickam, C., Kroll, K., Mosher, M., Reeves, R. K., Gam, R., Arthofer, E., Choudhry, M., Henley, T., & Barouch, D. H. (2022). A genetically engineered, stem-cell-derived cellular vaccine. Cell reports. Medicine, 3(12), 100843. https://doi.org/10.1016/j.xcrm.2022.100843
[Article]
Yu, J., Thomas, P. V., McMahan, K., Jacob-Dolan, C., Liu, J., He, X., Hope, D., Martinez, E. J., Chen, W. H., Sciacca, M., Hachmann, N. P., Lifton, M., Miller, J., Powers, O. C., Hall, K., Wu, C., Barrett, J., Swafford, I., Currier, J. R., King, J., … Barouch, D. H. (2022). Protection against SARS-CoV-2 Omicron BA.1 variant challenge in macaques by prime-boost vaccination with Ad26.COV2.S and SpFN. Science advances, 8(47), eade4433. https://doi.org/10.1126/sciadv.ade4433
[Article]
Stieh, D. J., Barouch, D. H., Comeaux, C., Sarnecki, M., Stephenson, K. E., Walsh, S. R., Sawant, S., Heptinstall, J., Tomaras, G. D., Kublin, J. G., McElrath, M. J., Cohen, K. W., De Rosa, S. C., Alter, G., Ferrari, G., Montefiori, D., Mann, P., Nijs, S., Callewaert, K., Goepfert, P. A., … Tomaka, F. (2022). Safety and Immunogenicity of Ad26-vectored HIV Vaccine with Mosaic Immunogens and a Novel Mosaic Envelope Protein in HIV-uninfected Adults: A Phase 1/2a Study. The Journal of infectious diseases, jiac445. Advance online publication. https://doi.org/10.1093/infdis/jiac445
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Dagotto, G., Ventura, J. D., Martinez, D. R., Anioke, T., Chung, B. S., Siamatu, M., Barrett, J., Miller, J., Schäfer, A., Yu, J., Tostanoski, L. H., Wagh, K., Baric, R. S., Korber, B., & Barouch, D. H. (2022). Immunogenicity and protective efficacy of a rhesus adenoviral vaccine targeting conserved COVID-19 replication transcription complex. NPJ vaccines, 7(1), 125. https://doi.org/10.1038/s41541-022-00553-2
[Article]
Hachmann, N. P., Miller, J., Collier, A. Y., & Barouch, D. H. (2022). Neutralization Escape by SARS-CoV-2 Omicron Subvariant BA.4.6. The New England journal of medicine, 387(20), 1904–1906. https://doi.org/10.1056/NEJMc2212117
[Article]
Barouch D. H. (2022). Covid-19 Vaccines - Immunity, Variants, Boosters. The New England journal of medicine, 387(11), 1011–1020. https://doi.org/10.1056/NEJMra2206573
[Article]
Singh PK, Li W, Bedwell GJ, Fadel HJ, Poeschla EM, Engelman AN. Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors. Viruses. 2022; 14(9):1883. https://doi.org/10.3390/v14091883
[Article]
Liu J, Yu J, McMahan K, Jacob-Dolan C, He X, Giffin V, Wu C, Sciacca M, Powers O, Nampanya F, Miller J, Lifton M, Hope D, Hall K, Hachmann NP, Chung B, Anioke T, Li W, Muench J, Gamblin A, Boursiquot M, Cook A, Lewis MG, Andersen H, Barouch DH. CD8 T Cells Contribute to Vaccine Protection Against SARS-CoV-2 in Macaques. Sci Immunol. 2022 Aug 9:eabq7647. doi: 10.1126/sciimmunol.abq7647. Epub ahead of print. PMID: 35943359.
[Article]
Valsecchio C, Winterton D, Fakhr BS, Collier AY, Nozari A, Ortoleva J, Mukerji S, Gibson LE, Carroll RW, Shaefi S, Pinciroli R, La Vita C, Ackman JB, Hohmann E, Arora P, Barth WH, Kaimal A, Ichinose F, Berra L;DELivery oF iNO (DELFINO) Network Collaborators. High-Dose Inhaled Nitric Oxide for the Treatment of Spontaneously Breathing Pregnant Patients With Severe Coronavirus Disease 2019 Pneumonia. Obstet Gynecol. April 2022. Accepted
Tan CS, Collier AY,Yu J, Liu J, Chandrashekar A, McMahan KA, Jacob-Dolan C, He X, Roy V, Hauser BM, Munt JE, Mallory ML, Mattocks M, Powers JM, Meganck RM, Rowe M, Hemond R, Bondzie EA, Jaegle KH, Baric RS, Schmidt AG, Alter G, Le Gars M, Sadoff J, Barouch DH. Durability of Heterologous and Homologous COVID-19 Vaccine Boost Regimens. JAMA Network Open. June 2022. Accepted.
Hachmann NP, Miller J, Collier AY, Ventura JD, Yu J, Rowe M, Bondzie EA, Powers O, Surve N, Hall K, Barouch DH. Neutralization Escape by SARS-CoV-2 Omicron Subvariants BA.2.12.1, BA.4, and BA.5. N Engl J Med. 2022 Jun 22. doi: 10.1056/NEJMc2206576. Epub ahead of print. PMID: 35731894.
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Moldt B, Chandrashekar A, Borducchi EN, Nkolola JP, Stephenson H, Nagel M, Hung M, Goldsmith J, Pace CS, Carr B, Thomsen ND, Blair WS, Geleziunas R, Barouch DH. HIV envelope antibodies and TLR7 agonist partially prevent viral rebound in chronically SHIV-infected monkeys. PLoS Pathog. 2022 Apr 22;18(4):e1010467. doi: 10.1371/journal.ppat.1010467. Epub ahead of print. PMID: 35452496.
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Collier AY, Brown CM, McMahan KA, Yu J, Liu J, Jacob-Dolan C, Chandrashekar A, Tierney D, Ansel JL, Rowe M, Sellers D, Ahmad K, Aguayo R, Anioke T, Gardner S, Siamatu M, Bermudez-Rivera L, Hacker MR, Madoff LC, Barouch DH. Characterization of immune responses in fully vaccinated individuals after breakthrough infection with the SARS-CoV-2 delta variant. Sci Transl Med. 2022 Apr 20;14(641):eabn6150. doi: 10.1126/scitranslmed.abn6150. Epub 2022 Apr 20. PMID: 35258323; PMCID: PMC8995036.
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DeGrace MM, Ghedin E, Frieman MB, Krammer F, Grifoni A, Alisoltani A, Alter G, Amara RR, Baric RS, Barouch DH, Bloom JD, Bloyet LM, Bonenfant G, Boon ACM, Boritz EA, Bratt DL, Bricker TL, Brown L, Buchser WJ, Carreño JM, Cohen-Lavi L, Darling TL, Davis-Gardner ME, Dearlove BL, Di H, Dittmann M, Doria-Rose NA, Douek DC, Drosten C, Edara VV, Ellebedy A, Fabrizio TP, Ferrari G, Florence WC, Fouchier RAM, Franks J, García-Sastre A, Godzik A, Gonzalez-Reiche AS, Gordon A, Haagmans BL, Halfmann PJ, Ho DD, Holbrook MR, Huang Y, James SL, Jaroszewski L, Jeevan T, Johnson RM, Jones TC, Joshi A, Kawaoka Y, Kercher L, Koopmans MPG, Korber B, Koren E, Koup RA, LeGresley EB, Lemieux JE, Liebeskind MJ, Liu Z, Livingston B, Logue JP, Luo Y, McDermott AB, McElrath MJ, Meliopoulos VA, Menachery VD, Montefiori DC, Mühlemann B, Munster VJ, Munt JE, Nair MS, Netzl A, Niewiadomska AM, O'Dell S, Pekosz A, Perlman S, Pontelli MC, Rockx B, Rolland M, Rothlauf PW, Sacharen S, Scheuermann RH, Schmidt SD, Schotsaert M, Schultz-Cherry S, Seder RA, Sedova M, Sette A, Shabman RS, Shen X, Shi PY, Shukla M, Simon V, Stumpf S, Sullivan NJ, Thackray LB, Theiler J, Thomas PG, Trifkovic S, Türeli S, Turner SA, Vakaki MA, van Bakel H, VanBlargan LA, Vincent LR, Wallace ZS, Wang L, Wang M, Wang P, Wang W, Weaver SC, Webby RJ, Weiss CD, Wentworth DE, Weston SM, Whelan SPJ, Whitener BM, Wilks SH, Xie X, Ying B, Yoon H, Zhou B, Hertz T, Smith DJ, Diamond MS, Post DJ, Suthar MS. Defining the risk of SARS-CoV-2 variants on immune protection. Nature. 2022 Mar 31. doi: 10.1038/s41586-022-04690-5. Epub ahead of print. PMID: 35361968.
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Kaplonek P, Cizmeci D, Fischinger S, Collier AR, Suscovich T, Linde C, Broge T, Mann C, Amanat F, Dayal D, Rhee J, de St Aubin M, Nilles EJ, Musk ER, Menon AS, Saphire EO, Krammer F, Lauffenburger DA, Barouch DH, Alter G. mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions. Sci Transl Med. 2022 Mar 29:eabm2311. doi: 10.1126/scitranslmed.abm2311. Epub ahead of print. PMID: 35348368; PMCID: PMC8995030.
[Article]
Chandrashekar A, Yu J, McMahan K, Jacob-Dolan C, Liu J, He X, Hope D, Anioke T, Barrett J, Chung B, Hachmann NP, Lifton M, Miller J, Powers O, Sciacca M, Sellers D, Siamatu M, Surve N, VanWyk H, Wan H, Wu C, Pessaint L, Valentin D, Van Ry A, Muench J, Boursiquot M, Cook A, Velasco J, Teow E, Boon ACM, Suthar MS, Jain N, Martinot AJ, Lewis MG, Andersen H, Barouch DH. Vaccine protection against the SARS-CoV-2 Omicron variant in macaques. Cell. 2022 Mar 17:S0092-8674(22)00334-8. doi: 10.1016/j.cell.2022.03.024. Epub ahead of print. PMID: 35427477; PMCID: PMC8926910.
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Yu J, Collier AY, Rowe M, Mardas F, Ventura JD, Wan H, Miller J, Powers O, Chung B, Siamatu M, Hachmann NP, Surve N, Nampanya F, Chandrashekar A, Barouch DH. Comparable Neutralization of the SARS-CoV-2 Omicron BA.1 and BA.2 Variants. medRxiv [Preprint]. 2022 Feb 7:2022.02.06.22270533. doi: 10.1101/2022.02.06.22270533. Update in: N Engl J Med. 2022 Mar 16;: PMID: 35169817; PMCID: PMC8845515.
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Dalvie NC, Tostanoski LH, Rodriguez-Aponte SA, Kaur K, Bajoria S, Kumru OS, Martinot AJ, Chandrashekar A, McMahan K, Mercado NB, Yu J, Chang A, Giffin VM, Nampanya F, Patel S, Bowman L, Naranjo CA, Yun D, Flinchbaugh Z, Pessaint L, Brown R, Velasco J, Teow E, Cook A, Andersen H, Lewis MG, Camp DL, Silverman JM, Nagar GS, Rao HD, Lothe RR, Chandrasekharan R, Rajurkar MP, Shaligram US, Kleanthous H, Joshi SB, Volkin DB, Biswas S, Love JC, Barouch DH. SARS-CoV-2 receptor binding domain displayed on HBsAg virus-like particles elicits protective immunity in macaques. Sci Adv. 2022 Mar 18;8(11):eabl6015. doi: 10.1126/sciadv.abl6015. Epub 2022 Mar 16. PMID: 35294244; PMCID: PMC8926328.
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Singh PK, Bedwell GJ, Engelman AN. Spatial and Genomic Correlates of HIV-1 Integration Site Targeting. Cells. 2022 Feb 14;11(4):655. doi: 10.3390/cells11040655. PMID: 35203306; PMCID: PMC8869898.
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Sadoff J, Gray G, Vandebosch A, Cárdenas V, Shukarev G, Grinsztejn B, Goepfert PA, Truyers C, Van Dromme I, Spiessens B, Vingerhoets J, Custers J, Scheper G, Robb ML, Treanor J, Ryser MF, Barouch DH, Swann E, Marovich MA, Neuzil KM, Corey L, Stoddard J, Hardt K, Ruiz-Guiñazú J, Le Gars M, Schuitemaker H, Van Hoof J, Struyf F, Douoguih M; ENSEMBLE Study Group. Final Analysis of Efficacy and Safety of Single-Dose Ad26.COV2.S. N Engl J Med. 2022 Feb 9. doi: 10.1056/NEJMoa2117608. Epub ahead of print. PMID: 35139271.
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Cobb RR, Nkolola J, Gilchuk P, Chandrashekar A, Yu J, House RV, Earnhart CG, Dorsey NM, Hopkins SA, Snow DM, Chen RE, VanBlargan LA, Hechenblaickner M, Hoppe B, Collins L, Tomic MT, Nonet GH, Hackett K, Slaughter JC, Lewis M, Andersen H, Cook A, Diamond MS, Carnahan RH, Barouch DH, Crowe JE Jr. A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in cynomolgus macaques. Med (N Y). 2022 Feb 3. doi: 10.1016/j.medj.2022.01.004. Epub ahead of print. PMID: 35132398; PMCID: PMC8810411.
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Liu J, Chandrashekar A, Sellers D, Barrett J, Jacob-Dolan C, Lifton M, McMahan K, Sciacca M, VanWyk H, Wu C, Yu J, Collier AY, Barouch DH. Vaccines Elicit Highly Conserved Cellular Immunity to SARS-CoV-2 Omicron. Nature. 2022 Jan 31. doi: 10.1038/s41586-022-04465-y. Epub ahead of print. PMID: 35102312.
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Jacob-Dolan C, Barouch DH. COVID-19 Vaccines: Adenoviral Vectors. Annu Rev Med. 2022 Jan 27;73:41-54. doi: 10.1146/annurev-med-012621-102252. Epub 2021 Oct 5. PMID: 34609905; PMCID: PMC8795482.
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Yu J, Collins ND, Mercado NB, McMahan K, Chandrashekar A, Liu J, Anioke T, Chang A, Giffin VM, Hope DL, Sellers D, Nampanya F, Gardner S, Barrett J, Wan H, Velasco J, Teow E, Cook A, Van Ry A, Pessaint L, Andersen H, Lewis MG, Hofer C, Burke DS, Barkei EK, King HAD, Subra C, Bolton D, Modjarrad K, Michael NL, Barouch DH. Protective Efficacy of Gastrointestinal SARS-CoV-2 Delivery against Intranasal and Intratracheal SARS-CoV-2 Challenge in Rhesus Macaques. J Virol. 2022 Jan 26;96(2):e0159921. doi: 10.1128/JVI.01599-21. Epub 2021 Oct 27. PMID: 34705557; PMCID: PMC8791250.
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Tostanoski LH, Chandrashekar A, Patel S, Yu J, Jacob-Dolan C, Chang A, Powers OC, Sellers D, Gardner S, Barrett J, Sanborn O, Stephenson KE, Ansel JL, Jaegle K, Seaman MS, Porto M, Lok M, Spence B, Cayer K, Nase D, Holman S, Bradette H, Kar S, Andersen H, Lewis MG, Cox F, Tolboom JTBM, de Groot AM, Heerwegh D, Le Gars M, Sadoff J, Wegmann F, Zahn RC, Schuitemaker H, Barouch DH. Passive transfer of Ad26.COV2.S-elicited IgG from humans attenuates SARS-CoV-2 disease in hamsters. NPJ Vaccines. 2022 Jan 10;7(1):2. doi: 10.1038/s41541-021-00427-z. PMID: 35013325; PMCID: PMC8748674.
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Gebre MS, Rauch S, Roth N, Yu J, Chandrashekar A, Mercado NB, He X, Liu J, McMahan K, Martinot A, Martinez DR, Giffin T, Hope D, Patel S, Sellers D, Sanborn O, Barrett J, Liu X, Cole AC, Pessaint L, Valentin D, Flinchbaugh Z, Yalley-Ogunro J, Muench J, Brown R, Cook A, Teow E, Andersen H, Lewis MG, Boon ACM, Baric RS, Mueller SO, Petsch B, Barouch DH. Optimization of Non-Coding Regions for a Non-Modified mRNA COVID-19 Vaccine. Nature. 2021 Nov 18. doi: 10.1038/s41586-021-04231-6. Epub ahead of print. PMID: 34794169.
[Article]
2021
Kalinke U, Barouch DH, Rizzi R, Lagkadinou E, Türeci Ö, Pather S, Neels P. Clinical development and approval of COVID-19 vaccines. Expert Rev Vaccines. 2022 Feb 14. doi: 10.1080/14760584.2022.2042257. Epub ahead of print. PMID: 35157542.
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Vidal SJ, Bekerman E, Hansen D, Lu B, Wang K, Mwangi J, Rowe W, Campigotto F, Zheng J, Kato D, Chandrashekar A, Barrett J, Patel S, Wan H, Anioke T, Mercado NB, Nkolola JP, Ferguson MJ, Rinaldi WJ, Callebaut C, Blair W, Cihlar T, Geleziunas R, Yant SR, Barouch DH. Long-acting capsid inhibitor protects macaques from repeat SHIV challenges. Nature. 2022 Jan;601(7894):612-616. doi: 10.1038/s41586-021-04279-4. Epub 2021 Dec 7. PMID: 34875675; PMCID: PMC8753592.
[Article]
Collier AY, Yu J, McMahan K, Liu J, Chandrashekar A, Maron JS, Atyeo C, Martinez DR, Ansel JL, Aguayo R, Rowe M, Jacob-Dolan C, Sellers D, Barrett J, Ahmad K, Anioke T, VanWyk H, Gardner S, Powers O, Bondzie EA, Wan H, Baric RS, Alter G, Hacker MR, Barouch DH. Differential Kinetics of Immune Responses Elicited by Covid-19 Vaccines. N Engl J Med. 2021 Oct 15. doi: 10.1056/NEJMc2115596. Epub ahead of print. PMID: 34648703.
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Alter G, Yu J, Liu J, Chandrashekar A, Borducchi EN, Tostanoski LH, McMahan K, Jacob-Dolan C, Martinez DR, Chang A, Anioke T, Lifton M, Nkolola J, Stephenson KE, Atyeo C, Shin S, Fields P, Kaplan I, Robins H, Amanat F, Krammer F, Baric RS, Le Gars M, Sadoff J, de Groot AM, Heerwegh D, Struyf F, Douoguih M, van Hoof J, Schuitemaker H, Barouch DH. Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans. Nature. 2021 Aug;596(7871):268-272. doi: 10.1038/s41586-021-03681-2. Epub 2021 Jun 9. PMID: 34107529.
[Article]
O'Brien MP, Forleo-Neto E, Musser BJ, Isa F, Chan KC, Sarkar N, Bar KJ, Barnabas RV, Barouch DH, Cohen MS, Hurt CB, Burwen DR, Marovich MA, Hou P, Heirman I, Davis JD, Turner KC, Ramesh D, Mahmood A, Hooper AT, Hamilton JD, Kim Y, Purcell LA, Baum A, Kyratsous CA, Krainson J, Perez-Perez R, Mohseni R, Kowal B, DiCioccio AT, Stahl N, Lipsich L, Braunstein N, Herman G, Yancopoulos GD, Weinreich DM; Covid-19 Phase 3 Prevention Trial Team. Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19. N Engl J Med. 2021 Aug 4:NEJMoa2109682. doi: 10.1056/NEJMoa2109682. Epub ahead of print. PMID: 34347950; PMCID: PMC8362593.
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Bedwell GJ, Jang S, Li W, Singh PK, Engelman AN. rigrag: high-resolution mapping of genic targeting preferences during HIV-1 integration in vitro and in vivo. Nucleic Acids Res. 2021 Jul 21;49(13):7330-7346. doi: 10.1093/nar/gkab514. PMID: 34165568; PMCID: PMC8287940.
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Jones R, Kroll K, Broedlow C, Schifanella L, Smith S, Hueber B, Shah SV, Ram DR, Manickam C, Varner V, Klatt NR, Reeves RK. Probiotic supplementation reduces inflammatory profiles but does not prevent oral immune perturbations during SIV infection. Sci Rep. 2021 Jul 15;11(1):14507. doi: 10.1038/s41598-021-93918-x. PMID: 34267278; PMCID: PMC8282626.
Barouch DH, Stephenson KE, Sadoff J, Yu J, Chang A, Gebre M, McMahan K, Liu J, Chandrashekar A, Patel S, Le Gars M, de Groot AM, Heerwegh D, Struyf F, Douoguih M, van Hoof J, Schuitemaker H. Durable Humoral and Cellular Immune Responses 8 Months after Ad26.COV2.S Vaccination. N Engl J Med. 2021 Jul 14:NEJMc2108829. doi: 10.1056/NEJMc2108829. Epub ahead of print. PMID: 34260834; PMCID: PMC8314733.
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Vidal SJ, Collier AY, Yu J, McMahan K, Tostanoski LH, Ventura JD, Aid M, Peter L, Jacob-Dolan C, Anioke T, Chang A, Wan H, Aguayo R, Ngo D, Gerszten RE, Seaman MS, Barouch DH. Correlates of Neutralization against SARS-CoV-2 Variants of Concern by Early Pandemic Sera. J Virol. 2021 Jun 24;95(14):e0040421. doi: 10.1128/JVI.00404-21. Epub 2021 Jun 24. PMID: 33893169.
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Collier AY, McMahan K, Yu J, Tostanoski LH, Aguayo R, Ansel J, Chandrashekar A, Patel S, Apraku Bondzie E, Sellers D, Barrett J, Sanborn O, Wan H, Chang A, Anioke T, Nkolola J, Bradshaw C, Jacob-Dolan C, Feldman J, Gebre M, Borducchi EN, Liu J, Schmidt AG, Suscovich T, Linde C, Alter G, Hacker MR, Barouch DH. Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women. JAMA. 2021 06 15; 325(23):2370-2380. PMID: 33983379.
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Sadoff J, Gray G, Vandebosch A, Cárdenas V, Shukarev G, Grinsztejn B, Goepfert PA, Truyers C, Fennema H, Spiessens B, Offergeld K, Scheper G, Taylor KL, Robb ML, Treanor J, Barouch DH, Stoddard J, Ryser MF, Marovich MA, Neuzil KM, Corey L, Cauwenberghs N, Tanner T, Hardt K, Ruiz-Guiñazú J, Le Gars M, Schuitemaker H, Van Hoof J, Struyf F, Douoguih M; ENSEMBLE Study Group. Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19. N Engl J Med. 2021 Jun 10;384(23):2187-2201. doi: 10.1056/NEJMoa2101544. Epub 2021 Apr 21. PMID: 33882225.
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Williams WB, Meyerhoff RR, Edwards RJ, Li H, Manne K, Nicely NI, Henderson R, Zhou Y, Janowska K, Mansouri K, Gobeil S, Evangelous T, Hora B, Berry M, Abuahmad AY, Sprenz J, Deyton M, Stalls V, Kopp M, Hsu AL, Borgnia MJ, Stewart-Jones GBE, Lee MS, Bronkema N, Moody MA, Wiehe K, Bradley T, Alam SM, Parks RJ, Foulger A, Oguin T, Sempowski GD, Bonsignori M, LaBranche CC, Montefiori DC, Seaman M, Santra S, Perfect J, Francica JR, Lynn GM, Aussedat B, Walkowicz WE, Laga R, Kelsoe G, Saunders KO, Fera D, Kwong PD, Seder RA, Bartesaghi A, Shaw GM, Acharya P, Haynes BF. Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell. 2021 May 27;184(11):2955-2972.e25. doi: 10.1016/j.cell.2021.04.042. Epub 2021 May 20. PMID: 34019795; PMCID: PMC8135257.
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Yu J, Li Z, He X, Gebre MS, Bondzie EA, Wan H, Jacob-Dolan C, Martinez DR, Nkolola JP, Baric RS, Barouch DH. Deletion of the SARS-CoV-2 Spike Cytoplasmic Tail Increases Infectivity in Pseudovirus Neutralization Assays. J Virol. 2021 Mar 16;95(11):e00044-21. doi: 10.1128/JVI.00044-21. Epub ahead of print. PMID: 33727331; PMCID: PMC8139703.
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Stephenson KE, Le Gars M, Sadoff J, de Groot AM, Heerwegh D, Truyers C, Atyeo C, Loos C, Chandrashekar A, McMahan K, Tostanoski LH, Yu J, Gebre MS, Jacob-Dolan C, Li Z, Patel S, Peter L, Liu J, Borducchi EN, Nkolola JP, Souza M, Tan CS, Zash R, Julg B, Nathavitharana RR, Shapiro RL, Azim AA, Alonso CD, Jaegle K, Ansel JL, Kanjilal DG, Guiney CJ, Bradshaw C, Tyler A, Makoni T, Yanosick KE, Seaman MS, Lauffenburger DA, Alter G, Struyf F, Douoguih M, Van Hoof J, Schuitemaker H, Barouch DH. Immunogenicity of the Ad26.COV2.S Vaccine for COVID-19. JAMA. 2021 Mar 11:e213645. doi: 10.1001/jama.2021.3645. Epub ahead of print. PMID: 33704352; PMCID: PMC7953339.
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Jacob-Dolan C, Feldman J, McMahan K, Yu J, Zahn R, Wegmann F, Schuitemaker H, Schmidt AG, Barouch DH. Coronavirus-Specific Antibody Cross Reactivity in Rhesus Macaques Following SARS-CoV-2 Vaccination and Infection. J Virol. 2021 Mar 10:JVI.00117-21. doi: 10.1128/JVI.00117-21. Epub ahead of print. PMID: 33692201.
[Article]
Cadena AM, Ventura JD, Abbink P, Borducchi EN, Tuyishime H, Mercado NB, Walker-Sperling V, Siamatu M, Liu PT, Chandrashekar A, Nkolola JP, McMahan K, Kordana N, Hamza V, Bondzie EA, Fray E, Kumar M, Fischinger S, Shin SA, Lewis MG, Siliciano RF, Alter G, Barouch DH. Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques. Nat Commun. 2021 Mar 5;12(1):1474. doi: 10.1038/s41467-021-21724-0. PMID: 33674572.
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