Jonathan Gootenberg

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Jonathan Gootenberg

Principal Investigator
Gootenberg Laboratory
jgootenb@bidmc.harvard.edu

Education

Massachusetts Institute of Technology, Cambridge, MA, B.S. 2013 ( Mathematics and Biological Engineering)

Harvard University Cambridge, MA. Ph.D., 2018 (Systems Biology)

Training

2019-2023 McGovern Fellow, Massachusetts Institute of Technology Cambridge, MA

Appointments

2023-present Staff Scientist, Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center

2023-Present, Assistant Professor, Harvard Medical School

Honors

2011- Lockheed Martin UROP Scholar, MIT
2012- John Reed UROP Scholar, MIT
2012- Tau Beta Pi honor society membership, MIT
2013- Award for outstanding service to the biological engineering community at MIT
2013- John and Fannie Hertz Fellowship, Finalist, Hertz Foundation
2014- John and Fannie Hertz Fellowship, Finalist, Hertz Foundation
2014- National Defense Science and Engineering Fellowship, awarded, Department of Defense
2014- National Science Foundation Graduate Research Fellowship Program, awarded, National Science Foundation
2014- Department of Energy Computational Science Graduate Fellowship, recipient, Department of Energy
2015- OneStart Life Sciences and Healthcare startup competition semi-finalist, SR One Capital Management
2017- TEDMED, Hive Innovator
2017- Academy of Achievement, delegate
2017- Forbes 30 Under 30, healthcare category, Forbes
2018- Business Insider 30 and Under 30, Business Insider
2021- Technology Review 35 under 35, MIT Technology Review
2022- Endpoints 20 under 40, Endpoints News
2022- Henri Termeer Scholar, Termeer Foundation

Publications

  • Jiang, K., Gootenberg, J. S., & Abudayyeh, O. O. (2025). Fanzors, a family of eukaryotic RNA-guided DNA endonucleases. FEBS letters, 599(8), 1089–1093. https://doi.org/10.1002/1873-3468.70038 [Article]

  • Fell CW, Villiger L, Lim J, Hiraizumi M, Tagliaferri D, Yarnall MTN, Lee A, Jiang K, Kayabolen A, Krajeski RN, Schmitt-Ulms C, Ramani H, Yousef SM, Roberts N, Vakulskas CA, Nishimasu H, Abudayyeh OO, Gootenberg JS. Reprogramming site-specific retrotransposon activity to new DNA sites. Nature. 2025 Jun;642(8069):1080-1089. doi: 10.1038/s41586-025-08877-4. Epub 2025 Apr 9. [Article]

  • Fell CW, Schmitt-Ulms C, Tagliaferri DV, Gootenberg JS, Abudayyeh OO. Precise kilobase-scale genomic insertions in mammalian cells using PASTE. Nature Protocols. 2025 Jun;20(6):1546-1583. doi: 10.1038/s41596-024-01090-z. Epub 2024 Dec 15. [Article]