Flow Cytometry Core
HIV-1 Neutralizing Antibody Core
The HIV-1 Neutralizing Antibody Core provides in vitro HIV-1 neutralizing antibody assay services to BIDMC and the external research community. The core is GCLP-compliant; it serves as a resource for assessing the breadth and potency of HIV-1 neutralizing antibodies, and for characterizing the neutralization phenotype of HIV-1 isolates.
Investigators send monoclonal antibodies or serum samples from vaccinated or HIV-1-infected individuals to the core for in vitro testing using the validated TZM.bl neutralizing antibody assay. The core also has the capability to phenotype primary HIV-1 isolates for sensitivity to broadly neutralizing antibodies.
Harvard Catalyst Clinical Research Center
The Harvard Catalyst Clinical Research Center (CRC) is a core facility provided to all BIDMC investigators as well as affiliated Harvard faculty for the conduct of clinical trials. The CRC provides contiguous space for inpatient, outpatient, and administrative support activities and is located on the 8th floors of the Gryzmish and Feldberg buildings at BIDMC.
The outpatient area consists of 12 rooms, including two general purpose rooms with beds and private bathrooms, one examination/minor procedure room, one interview room, and a room equipped for neurological testing, among other rooms. The inpatient unit consists of 8 beds in two double rooms and four single rooms. The unit is open for patient activity 24 hours per day, seven days per week.
CRC staff includes nurses, dieticians, a laboratory assistant, and a unit coordinator. Access to administrative space includes a conference room, investigator’s resource room, and use of the statistical programs on three computers located near the statistician’s office.
Learn more at https://catalyst.harvard.edu/