JIangSizun Jiang CVVR

Sizun Jiang,Ph.D.

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Sizun Jiang,Ph.D.

Principal Investigator
Jiang Laboratory

Faculty, Beth Israel Deaconess Medical Center

sjiang3@bidmc.harvard.edu

Education

  • University of Wisconsin-Madison, Madison, WI, B.S. (Honors), 2012 (Molecular Biology)
  • Harvard University, Cambridge, MA, Ph.D., 2017 (Virology) (PI: Elliott Kieff)

Training

  • 2017-2021 Postdoctoral Research Fellow, Stanford University, Stanford, CA (PI: Garry Nolan)

Appointments

  • 2021 – present, Faculty, Beth Israel Deaconess Medical Center

Honors

  • 2009 – 2012, Agency of Science, Technology and Research (A*STAR) National Science Scholarship (Singapore)
  • 2010, Trewartha Senior Thesis Grant – One of ten awardees at College of L&S, UW-Madison
  • 2011, University of Wisconsin-Madison Library Research Award – Outstanding Thesis presented at the Annual Undergraduate Symposium
  • 2011, International Students Services/Wisconsin Alumni Association Academic Achievement Award – Awarded to international students who demonstrated excellence in academics
  • 2015 – 2017, Howard Hughes Medical Institute (HHMI) International Fellowship – One of forty-two recipients in the USA to support graduate research
  • 2015, Certificate of Teaching Excellence, Harvard University
  • 2016, Van Andel Research Institute Epigenomics Course Scholarship
  • 2016, Best Poster at Abcam Boston Chromatin Snapshot series: Epigenome to single cell resolution
  • 2016, ChIA-PET Workshop on 3D Genome Mapping Technology Scholarship
  • 2017, Fields Prize in Microbiology and Immunobiology, Department of Microbiology, Harvard Medical School – The Harvard Department of Microbiology and Immunobiology awards this prize to our graduate or medical students who best exemplify the virtues of intellectual creativity, collegiality, and compassion displayed by the Department’s late Chair, Bernard N. Fields
  • 2018, Stanford School of Medicine Dean’s Postdoctoral Fellowship
  • 2018, Keystone Symposia Scholarship in Chromatin Architecture and Chromosome Organization
  • 2018 – 2021, Leukemia and Lymphoma Society Career Development Fellow
  • 2021, Stanford Bio-X Travel Award

Publications

  • Bernard E, Cortés-Ciriano I, Gaiti F, Gan S, Jiang S, Kovatcheva M, Meisel M, Reticker-Flynn NE, Schram AM, Shoshani O, Silverbush D, Venkataramani V, Weeden CE, Zhou X. Reflections on Advances in Cancer Research in 2025. Cancer Discov. 2025 Dec 2;15(12):2422-2430. doi: 10.1158/2159-8290.CD-25-1833. PMID: 41327969. [Article]

  • Wang H, Mou Z, Yeo YY, Ge Q, Liu X, Narita Y, Li Z, Wang C, Li W, Zhao KR, Li J, Bu W, Gewurz B, Cohen JI, Teng M, Dai X, Liu X, Jiang S, Zhao B. Epstein-Barr virus exploits desmocollin 2 as the principal epithelial cell entry receptor. Nat Microbiol. 2025 Nov;10(11):2781-2796. doi: 10.1038/s41564-025-02126-0. Epub 2025 Sep 26. PMID: 41006833. [Article]

  • Lu Y, Dai H, Tang H, Donahoo WT, George TJ, Sun RC, Jiang S, Tan AC, Guo Y, Licht JD, Allen JM, Lee KP, Guo J, Bian J. Association of Glucagon-Like Peptide-1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes. Obesity (Silver Spring). 2025 Aug 21. doi: 10.1002/oby.24366. [Article]

  • Liu SX, Wu TW, Luo DH, Zhang LL, Zhou L, Luo YL, Du WT, Huang TT, Jiang S, Zhang Z, Han P, Zeng MS, Zhong Q. Interferon-responsive HEVs drive tumor tertiary lymphoid structure formation and predict immunotherapy response in nasopharyngeal carcinoma. Cell Reports Medicine. 2025 Jul 15;6(7):102200. doi: 10.1016/j.xcrm.2025.102200. Epub 2025 Jun 20. [Article]

  • Aliazis K, Christofides A, Shah R, Yeo YY, Jiang S, Charest A, Boussiotis VA. The tumor microenvironment's role in the response to immune checkpoint blockade. Nature Cancer. 2025 Jun;6(6):924-937. doi: 10.1038/s43018-025-00986-3. Epub 2025 Jun 13. [Article]

  • Zhang L, Cagle C, Nguyen DH, Gomes GS, Gromova B, Csizmadia E, Karimitar A, Lee GR, Chen G, Kokkotou E, Grossberg L, Jiang S, Cheifetz AS, Kota SK, Longhi MS. Antisense to human CD39 dysregulates immune metabolism in inflammatory bowel disease. Cellular Molecular Immunology. 2025 Jul;22(7):730-742. doi: 10.1038/s41423-025-01295-6. Epub 2025 May 26. [Article]

  • Zhu B, Gao S, Chen S, Wang Y, Yeung J, Bai Y, Huang AY, Yeo YY, Liao G, Mao S, Jiang ZG, Rodig SJ, Wong KC, Shalek AK, Nolan GP, Jiang S, Ma Z. CellLENS enables cross-domain information fusion for enhanced cell population delineation in single-cell spatial omics data. Nature Immunology. 2025 Jun;26(6):963-974. doi: 10.1038/s41590-025-02163-1. Epub 2025 May 22. [Article]

  • Hahn, K., Amberg, B., Monné Rodriguez, J. M., Verslegers, M., Kang, B., Wils, H., Saravanan, C., Bangari, D. S., Long, S. Y., Youssef, S. A., Pesti, B., Schaffenrath, J., Valdeolivas, A., Kumpesa, N., Galván, J. A., Richardson, M., Giroud, N., Kunz, L., Veiga, I. B., Bscheider, M., … Jacobsen, B. (2025). Points to Consider From the ESTP Pathology 2.0 Working Group: Overview on Spatial Omics Technologies Supporting Drug Discovery and Development. Toxicologic pathology, 53(1), 107–129. doi: 10.1177/01926233241311258 [Article]

  • Zhu B, Bai Y, Yeo YY, Lu X, Rovira-Clavé X, Chen H, Yeung J, Nkosi D, Glickman J, Delgado-Gonzalez A, Gerber GK, Angelo M, Shalek AK, Nolan GP, Jiang S. A multi-omics spatial framework for host-microbiome dissection within the intestinal tissue microenvironment. Nat Commun. 2025 Jan 31;16(1):1230. doi: 10.1038/s41467-025-56237-7. PMID: 39890778; PMCID: PMC11785740. [Article]

  • Chang, Y., Liu, J., Jiang, Y., Ma, A., Yeo, Y. Y., Guo, Q., McNutt, M., Krull, J. E., Rodig, S. J., Barouch, D. H., Nolan, G. P., Xu, D., Jiang, S., Li, Z., Liu, B., & Ma, Q. (2024). Graph Fourier transform for spatial omics representation and analyses of complex organs. Nature communications, 15(1), 7467. https://doi.org/10.1038/s41467-024-51590-5 [Article]