JIangSizun Jiang CVVR

Sizun Jiang,Ph.D.

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Sizun Jiang,Ph.D.

Principal Investigator
Jiang Laboratory

Faculty, Beth Israel Deaconess Medical Center

sjiang3@bidmc.harvard.edu

Education

  • University of Wisconsin-Madison, Madison, WI, B.S. (Honors), 2012 (Molecular Biology)
  • Harvard University, Cambridge, MA, Ph.D., 2017 (Virology) (PI: Elliott Kieff)

Training

  • 2017-2021 Postdoctoral Research Fellow, Stanford University, Stanford, CA (PI: Garry Nolan)

Appointments

  • 2021 – present, Faculty, Beth Israel Deaconess Medical Center

Honors

  • 2009 – 2012, Agency of Science, Technology and Research (A*STAR) National Science Scholarship (Singapore)
  • 2010, Trewartha Senior Thesis Grant – One of ten awardees at College of L&S, UW-Madison
  • 2011, University of Wisconsin-Madison Library Research Award – Outstanding Thesis presented at the Annual Undergraduate Symposium
  • 2011, International Students Services/Wisconsin Alumni Association Academic Achievement Award – Awarded to international students who demonstrated excellence in academics
  • 2015 – 2017, Howard Hughes Medical Institute (HHMI) International Fellowship – One of forty-two recipients in the USA to support graduate research
  • 2015, Certificate of Teaching Excellence, Harvard University
  • 2016, Van Andel Research Institute Epigenomics Course Scholarship
  • 2016, Best Poster at Abcam Boston Chromatin Snapshot series: Epigenome to single cell resolution
  • 2016, ChIA-PET Workshop on 3D Genome Mapping Technology Scholarship
  • 2017, Fields Prize in Microbiology and Immunobiology, Department of Microbiology, Harvard Medical School – The Harvard Department of Microbiology and Immunobiology awards this prize to our graduate or medical students who best exemplify the virtues of intellectual creativity, collegiality, and compassion displayed by the Department’s late Chair, Bernard N. Fields
  • 2018, Stanford School of Medicine Dean’s Postdoctoral Fellowship
  • 2018, Keystone Symposia Scholarship in Chromatin Architecture and Chromosome Organization
  • 2018 – 2021, Leukemia and Lymphoma Society Career Development Fellow
  • 2021, Stanford Bio-X Travel Award

Publications

  • Zhu B, Bai Y, Yeo YY, Lu X, Rovira-Clavé X, Chen H, Yeung J, Nkosi D, Glickman J, Delgado-Gonzalez A, Gerber GK, Angelo M, Shalek AK, Nolan GP, Jiang S. A multi-omics spatial framework for host-microbiome dissection within the intestinal tissue microenvironment. Nat Commun. 2025 Jan 31;16(1):1230. doi: 10.1038/s41467-025-56237-7. PMID: 39890778; PMCID: PMC11785740. [Article]

  • Chang, Y., Liu, J., Jiang, Y., Ma, A., Yeo, Y. Y., Guo, Q., McNutt, M., Krull, J. E., Rodig, S. J., Barouch, D. H., Nolan, G. P., Xu, D., Jiang, S., Li, Z., Liu, B., & Ma, Q. (2024). Graph Fourier transform for spatial omics representation and analyses of complex organs. Nature communications, 15(1), 7467. https://doi.org/10.1038/s41467-024-51590-5 [Article]

  • Jiang, S. PANINI: Combined protein and nucleic acid imaging in tissues. Nat Rev Immunol (2024). https://doi.org/10.1038/s41577-024-01028-2 [Article]

  • Yeo YY, Cramer P, Deisher A, Bai Y, Zhu B, Yeo WJ, Shipp MA, Rodig SJ, Jiang S. A Hitchhiker's guide to high-dimensional tissue imaging with multiplexed ion beam imaging. Methods Cell Biol. 2024;186:213-231. doi: 10.1016/bs.mcb.2024.02.018. Epub 2024 Mar 10. PMID: 38705600. [Article]

  • Gao L, Zhang W, Zhang L, Gromova B, Chen G, Csizmadia E, Cagle C, Nastasio S, Ma Y, Bonder A, Patwardhan V, Robson SC, Jiang S, Longhi MS. Silencing of aryl hydrocarbon receptor repressor restrains Th17 cell immunity in autoimmune hepatitis. J Autoimmun. 2024 Feb;143:103162. doi: 10.1016/j.jaut.2023.103162. Epub 2023 Dec 23. PMID: 38142533; PMCID: PMC10981568. [Article]

  • Song NJ, Chakravarthy KB, Jeon H, Bolyard C, Reynolds K, Weller KP, Reisinger S, Wang Y, Li A, Jiang S, Ma Q, Barouch DH, Rubinstein MP, Shields PG, Oltz EM, Chung D, Li Z. mRNA vaccines against SARS-CoV-2 induce divergent antigen-specific T-cell responses in patients with lung cancer. J Immunother Cancer. 2024 Jan 4;12(1):e007922. doi: 10.1136/jitc-2023-007922. PMID: 38177076; PMCID: PMC10773442.
    [Article]

  • Shaban M, Bai Y, Qiu H, Mao S, Yeung J, Yeo YY, Shanmugam V, Chen H, Zhu B, Weirather JL, Nolan GP, Shipp MA, Rodig SJ, Jiang S, Mahmood F. MAPS: pathologist-level cell type annotation from tissue images through machine learning. Nat Commun. 2024 Jan 2;15(1):28. doi: 10.1038/s41467-023-44188-w. PMID: 38167832; PMCID: PMC10761896. [Article]

  • Patel AG, Ashenberg O, Collins NB, Segerstolpe Å, Jiang S, Slyper M, Huang X, Caraccio C, Jin H, Sheppard H, Xu K, Chang TC, Orr BA, Shirinifard A, Chapple RH, Shen A, Clay MR, Tatevossian RG, Reilly C, Patel J, Lupo M, Cline C, Dionne D, Porter CBM, Waldman J, Bai Y, Zhu B, Barrera I, Murray E, Vigneau S, Napolitano S, Wakiro I, Wu J, Grimaldi G, Dellostritto L, Helvie K, Rotem A, Lako A, Cullen N, Pfaff KL, Karlström Å, Jané-Valbuena J, Todres E, Thorner A, Geeleher P, Rodig SJ, Zhou X, Stewart E, Johnson BE, Wu G, Chen F, Yu J, Goltsev Y, Nolan GP, Rozenblatt-Rosen O, Regev A, Dyer MA. A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity. bioRxiv [Preprint]. 2024 Jan 16:2024.01.07.574538. doi: 10.1101/2024.01.07.574538. PMID: 38260392; PMCID: PMC10802404. [Article]