Malika Aid-Boudries, Ph.D.

Dr. Aid-Boudries is an Assistant professor of Medicine at the Center for Virology and Vaccine Research (CVVR). She received her Ph.D. in Computational Biology and Bioinformatics from the Center for Immunology and Cancer at the University of Montreal, Quebec, Canada. At CVVR, her research focuses on developing computational pipelines and machine learning-based approaches (ML/AI) to investigate OMICS signatures associated with disease pathogenesis, baseline and post-vaccination predictor biomarkers of vaccines immunogenicity, and durability. Dr. Boudries is also exploring disease pathogenesis through epigenetics profiling, with a keen interest in decoding the epigenetics determinant of HIV integration and the latent HIV reservoir maintenance and persistence.

Education

B.Sc., Computer Science engineering, 1995. UMMTO, Algeria

M.Sc., Biology, 2007. Department of Biochemistry, University of Montreal, Montreal, Canada

Ph.D., Computational Biology and Bioinformatics, 2014. Institute for Research in Immunology and cancer, University of Montreal, Montreal, Canada

Training

02/2014 – 12/2014   Research Fellow, Vaccine and Gene Therapy Institute of Florida/Case Western Reserve University, Cleveland, Ohio

2015 – 2018 Research Fellow, Harvard Medical School, Center for Virology and Vaccine Research, BIDMC, Boston, MA

2019 – 2022, Instructor in Medicine, Harvard Medical School, Center for Virology and Vaccine Research, BIDMC, Boston, MA

Appointments

2014-2015, Research Associate, CASE Western Reserve University School of Medicine, Cleveland, Ohio

2016-2019, Staff Scientist, Harvard Medical School, Center for Virology and Vaccine Research, BIDMC, Boston, MA

2019- 2022, Instructor in Medicine, Harvard Medical School, Center for Virology and Vaccine Research, BIDMC, Boston, MA

Honors

2010 – 2011, Biochemistry Department Excellence Scholarship, University of Montreal, Quebec, Canada

2007 – 2010, Excellence Scholarship for Ph.D. student, University of Montreal, Canada

2006 – 2007, Excellence Scholarship for Master’s Student, University of Montreal, Canada

2023-2025, Diversity Inclusion and Community Partnership (DICP) Faculty Fellowship Award

Publications

• Aid M, Stephenson KE, Collier AY, Nkolola JP, Michael JV, McKenzie SE, Barouch DH. Activation of coagulation and proinflammatory pathways in thrombosis with thrombocytopenia syndrome and following COVID-19 vaccination. Nat Commun. 2023 Oct 23;14(1):6703. doi: 10.1038/s41467-023-42559-x. PMID: 37872311; PMCID: PMC10593859. [Article]


• Aid M, Sciacca M, McMahan K, Hope D, Liu J, Jacob-Dolan C, Powers O, Barrett J, Wu C, Mutoni A, Murdza T, Richter H, Velasco J, Teow E, Boursiquot M, Cook A, Orekov T, Hamilton M, Pessaint L, Ryan A, Hayes T, Martinot AJ, Seaman MS, Lewis MG, Andersen H, Barouch DH. Mpox infection protects against re-challenge in rhesus macaques. Cell. 2023 Oct 12;186(21):4652-4661.e13. doi: 10.1016/j.cell.2023.08.023. Epub 2023 Sep 20. PMID: 37734373; PMCID: PMC10591870. [Article]


• Vidal SJ, Sellers D, Yu J, Wakabayashi S, Sixsmith J, Aid M, Barrett J, Stevens SF, Liu X, Li W, Plumlee CR, Urdahl KB, Martinot AJ, Barouch DH. Attenuated Mycobacterium tuberculosis vaccine protection in a low-dose murine challenge model. iScience. 2023 May 28;26(6):106963. doi: 10.1016/j.isci.2023.106963. PMID: 37378347; PMCID: PMC10291467. [Article]