Malika Boudries, Ph.D.

Malika Boudries, Ph.D.

Instructor
Barouch Laboratory

Dr. Malika Aid did her undergraduate studies in computer science engineering.  Her engineering thesis was about the development of a mathematical model to predict meteorological changes using cloud distribution and density. She joined Dr Sylvie Mader’s team at the institute for research in immunology and cancer (IRIC) in Montreal for her master and Ph.D. in Bioinformatics.  She worked on the characterization of the transcriptional regulation mechanisms of estrogen receptor ERalpha. During her Ph.D., she developed a computational tool to predict transcription factors DNA binding sites using ChIP-Seq and ChIP-chip data. This software was then used to identify new transcriptional partners of estrogen receptor alpha and their downstream target genes. After her Ph.D., she joined Dr Sekaly’s group at VGTI Florida for her post-doc. During her two years post-doc position at Sekaly’s group, her work was focused on the development and implementation of system biology approaches to identify gene expression signatures that predict protection and acquisition from HIV and SIV infections. In 2016, she joined Dr. Dan Barouch laboratory at the Center for Virology and Vaccine Research and her ongoing research focuses on developing system biology approaches in order to understand the role of the innate and adaptive immune response with a focus on identifying gene expression signatures that predict response to vaccines.  She is also involved in other projects that aim to elucidate mechanisms that regulate the establishment/maintenance of HIV latency and therapeutic strategies currently under evaluation in order to eradicate HIV persistence.