A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV

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Sajadi, M. M., Abbasi, A., Tehrani, Z. R., Siska, C., Clark, R., Chi, W., Seaman, M. S., Mielke, D., Wagh, K., Liu, Q., Jumpa, T., Ketchem, R. R., Nguyen, D. N., Tolbert, W. D., Pierce, B. G., Atkinson, B., Deming, D., Sprague, M., Asakawa, A., Ferrer, D., … DeVico, A. (2025). A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV. Structure (London, England : 1993), 33(7), 1150–1164.e8. https://doi.org/10.1016/j.str.2025.04.016 [Article]