Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir

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Briganti, L., Annamalai, A. S., Bester, S. M., Wei, G., Andino-Moncada, J. R., Singh, S. P., Kleinpeter, A. B., Tripathi, M., Nguyen, B., Radhakrishnan, R., Singh, P. K., Greenwood, J., Schope, L. I., Haney, R., Huang, S.-W., Freed, E. O., Engelman, A. N., Francis, A. C., & Kvaratskhelia, M. (2025). Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir. mBio, 16(5), e0361324. https://doi.org/10.1128/mbio.03613-24 [Article]