B cell somatic hypermutation following COVID-19 vaccination with Ad26.COV2.S

Jacob-Dolan C, Lifton M, Powers OC, Miller J, Hachmann NP, Vu M, Surve N, Mazurek CR, Fisher JL, Rodrigues S, Patio RC, Anand T, Le Gars M, Sadoff J, Schmidt AG, Barouch DH. B cell somatic hypermutation following COVID-19 vaccination with Ad26.COV2.S. iScience. 2024 Apr 9;27(5):109716. doi: 10.1016/j.isci.2024.109716. PMID: 38655202; PMCID: PMC11035370.

COVID-19 vaccines: Immune correlates and clinical outcomes

Mahrokhian, S. H., Tostanoski, L. H., Vidal, S. J., & Barouch, D. H. (2024). COVID-19 vaccines: Immune correlates and clinical outcomes. Human Vaccines & Immunotherapeutics20(1). https://doi.org/10.1080/21645515.2024.2324549

Isolation of a recombinant simian adenovirus encoding the human adenovirus G52 hexon suggests a simian origin for human adenovirus G52

Pinski AN, Gan T, Lin S, Droit L, Diamond M, Barouch DH, Wang D.2024.Isolation of a recombinant simian adenovirus encoding the human adenovirus G52 hexon suggests a simian origin for human adenovirus G52. J Virol98:e00043-24.https://doi.org/10.1128/jvi.00043-24

A microneedle vaccine printer for thermostable COVID-19 mRNA vaccines

Vander Straeten A, Sarmadi M, Daristotle JL, Kanelli M, Tostanoski LH, Collins J, Pardeshi A, Han J, Varshney D, Eshaghi B, Garcia J, Forster TA, Li G, Menon N, Pyon SL, Zhang L, Jacob-Dolan C, Powers OC, Hall K, Alsaiari SK, Wolf M, Tibbitt MW, Farra R, Barouch DH, Langer R, Jaklenec A. A microneedle vaccine printer for thermostable COVID-19 mRNA vaccines. Nat Biotechnol. 2024 Mar;42(3):510-517. doi: 10.1038/s41587-023-01774-z. Epub 2023 Apr 24. PMID: 37095347; PMCID: PMC10593912.

Neutralization of SARS-CoV-2 Omicron subvariant BA.2.87.1

Lasrado N, Rössler A, Rowe M, Collier AY, Barouch DH. Neutralization of SARS-CoV-2 Omicron subvariant BA.2.87.1. Vaccine. 2024 Apr 2;42(9):2117-2121. doi: 10.1016/j.vaccine.2024.03.007. Epub 2024 Mar 7. PMID: 38458874.

Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer

Alsaiari SK, Nadeef S, Daristotle JL, Rothwell W, Du B, Garcia J, Zhang L, Sarmadi M, Forster TA, Menon N, Lin SQ, Tostanoski LH, Hachmann N, Wang EY, Ventura JD, Barouch DH, Langer R, Jaklenec A. Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer. Sci Adv. 2024 Mar 8;10(10):eadj6380. doi: 10.1126/sciadv.adj6380. Epub 2024 Mar 6. PMID: 38446889; PMCID: PMC10917347.

High Frequency of Prior Severe Acute Respiratory Syndrome Coronavirus 2 Infection by Sensitive Nucleocapsid Assays

Joseph P Nkolola, Jinyan Liu, Ai-ris Y Collier, Catherine Jacob-Dolan, Yasmeen Senussi, Ella Borberg, Zoe Swank, David R Walt, Dan H Barouch, High Frequency of Prior Severe Acute Respiratory Syndrome Coronavirus 2 Infection by Sensitive Nucleocapsid Assays, The Journal of Infectious Diseases, 2024;, jiae174, https://doi.org/10.1093/infdis/jiae174

Neutralization of SARS-CoV-2 Omicron subvariant BA.2.87.1

Lasrado N, Rössler A, Rowe M, Collier AY, Barouch DH. Neutralization of SARS-CoV-2 Omicron subvariant BA.2.87.1. Vaccine. 2024 Apr 2;42(9):2117-2121. doi: 10.1016/j.vaccine.2024.03.007. Epub 2024 Mar 7. PMID: 38458874.

Modeling resistance to the broadly neutralizing antibody PGT121 in people living with HIV-1

Cassidy T, Stephenson KE, Barouch DH, Perelson AS (2024) Modeling resistance to the broadly neutralizing antibody PGT121 in people living with HIV-1. PLOS Computational Biology 20(3): e1011518. https://doi.org/10.1371/journal.pcbi.1011518

Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques

Jacob-Dolan C, Ty D, Hope D, McMahan K, Liu J, Powers OC, Cotter CA, Sciacca M, Wu C, Borducchi E, Bouffard E, Richter H, Velasco J, Teow E, Boursiquot M, Cook A, Feliciano K, Yalley-Ogunro J, Seaman MS, Pessiant L, Lewis MG, Andersen H, Moss B, Barouch DH. Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques. Sci Transl Med. 2024 Mar 27;16(740):eadl4317. doi: 10.1126/scitranslmed.adl4317. Epub 2024 Mar 27. PMID: 38536937.