Probiotic supplementation reduces inflammatory profiles but does not prevent oral immune perturbations during SIV infection

Jones R, Kroll K, Broedlow C, Schifanella L, Smith S, Hueber B, Shah SV, Ram DR, Manickam C, Varner V, Klatt NR, Reeves RK. Probiotic supplementation reduces inflammatory profiles but does not prevent oral immune perturbations during SIV infection. Sci Rep. 2021 Jul 15;11(1):14507. doi: 10.1038/s41598-021-93918-x. PMID: 34267278; PMCID: PMC8282626.

TRIGGERED: could refocused cell signaling be key to natural killer cell-based HIV immunotherapeutics?

Delineation and Modulation of the Natural Killer Cell Transcriptome in Rhesus Macaques During ZIKV and SIV Infections

Aid, M., Ram, D. R., Bosinger, S. E., Barouch, D. H., & Reeves, R. K. (2020). Delineation and Modulation of the Natural Killer Cell Transcriptome in Rhesus Macaques During ZIKV and SIV Infections. Frontiers in Cellular and Infection Microbiology10. doi: 10.3389/fcimb.2020.00194

Functional Perturbation of Mucosal Group 3 Innate Lymphoid and Natural Killer Cells in Simian-Human Immunodeficiency Virus/Simian Immunodeficiency Virus-Infected Infant Rhesus Macaques.

Hueber, B., Curtis, A. D., Kroll, K., Varner, V., Jones, R., Pathak, S., … Reeves, R. K. (2020). Functional Perturbation of Mucosal Group 3 Innate Lymphoid and Natural Killer Cells in Simian-Human Immunodeficiency Virus/Simian Immunodeficiency Virus-Infected Infant Rhesus Macaques. Journal of Virology94(5). doi: 10.1128/jvi.01644-19

Silent damage? Occult HCV replication and histological disease may occur following apparent HCV clearance

Manickam C, Reeves RK. Silent damage? Occult HCV replication and histological disease may occur following apparent HCV clearance. EBioMedicine. 2019;47:12-13. doi:10.1016/j.ebiom.2019.08.029.

SIV infection modulates CD94(KLRD1)+ NK cells in rhesus macaques.

Ram DR, Lucar O, Hueber B, Reeves RK. 2019. SIV infection modulates CD94(KLRD1)+ NK cells in rhesus macaques. J. Virol. 93(16):e00731-19. PMID:31167916. PMCID: PMC6675877

Semaphorin 7A modulates cytokine-induced memory-like responses by human natural killer cells.

Ghofrani J, Lucar O, Dugan H, Reeves RK, Jost S. Semaphorin 7A modulates cytokine-induced memory-like responses by human natural killer cells. (2019) European Journal of Immunology. 49(8):1153-1166.

Non-linear multidimensional flow cytometry analyses delineate NK cell phenotypes in normal and HIV-infected chimpanzees.

Manickam, C., Li, H., Kroll, K., and Reeves, R.K. Non-linear multidimensional flow cytometry analyses delineate NK cell phenotypes in normal and HIV-infected chimpanzees. 2019. Int. Immunol. 5;31(3):175-180. PMID: 30418531. PMCID: PMC6400041

Monkeying around: Using nonhuman primate models to study NK cell biology in HIV infections.

Manickam, C., Shah, S., Nohara, J., Ferrari, G., Reeves, R.K. ­­­­2019 Monkeying around: Using nonhuman primate models to study NK cell biology in HIV infections. Front. Immunol. 10:1124. PMID: 31191520. PMCID: PMC6540610.

Memory and antigen-specific NK cell responses in HIV/SIV infections: A roadmap to cell-based therapeutics?

Ram, R., Manickam, C, Lucar, O., Shah, S., and Reeves, R.K. Memory and antigen-specific NK cell responses in HIV/SIV infections: A roadmap to cell-based therapeutics? 2019. J. Leukoc. Bio. 105(6):1253-1259. PMID: 30730588. PMID: 30730588. PMCID: PMC6536345