Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation.

Palmer CD, Romero-Tejeda M, Sirignano M, Sharma S, Allen TM, Altfeld M, Jost S. Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation. (2016) Journal of immunology.196(2):668-77.

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.

Garcia-Beltran WF, Holzemer A, Martrus G, Chung AW, Pacheco Y, Simoneau CR, Rucevic M, Lamothe-Molina PA, Pertel T, Kim TE, Dugan H, Alter G, Dechanet-Merville J, Jost S, Carrington M, Altfeld M. Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1. (2016) Nature immunology. 17(9):1067-74.

Antigen-specific NK cell memory in rhesus macaques.

Reeves RK, Li H, Jost S, Blass E, Li H, Schafer JL, Varner V, Manickam C, Eslamizar L, Altfeld M, Von Andrian UH, Barouch DH. Antigen-specific NK cell memory in rhesus macaques. Nat. Immunol. 2015; 16:927-932.

Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01.

Salzberger W, Garcia-Beltran WF, Dugan H, Gubbala S, Simoneau C, Gressens SB, Jost S, Altfeld M. Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01. (2015) PLoS One. 10(12):e0145324.

CD4+ T-cell help enhances NK cell function following therapeutic HIV-1 vaccination.

Jost S, Tomezsko PJ, Rands K, Toth I, Lichterfeld M, Gandhi RT, Altfeld M. CD4+ T-cell help enhances NK cell function following therapeutic HIV-1 vaccination. (2014) J Virol. 88(15):8349- 54.

Enhanced immune activation linked to endotoxemia in HIV-1 seronegative MSM.

Palmer CD, Tomassilli J, Sirignano M, Tejeda MR, Arnold KB, Che D, Lauffenburger DA, Jost S, Allen T, Mayer KH, Altfeld M. Enhanced immune activation linked to endotoxemia in HIV-1 seronegative MSM. (2014) AIDS. 28(14):2162-66.

Increased frequency and function of KIR2DL1-3(+) NK cells in primary HIV-1 infection are determined by HLA-C group haplotypes.

Korner C, Granoff ME, Amero MA, Sirignano MN, Vaidya SA, Jost S, Allen TM, Rosenberg ES, Altfeld M. Increased frequency and function of KIR2DL1-3(+) NK cells in primary HIV-1 infection are determined by HLA-C group haplotypes. (2014) European journal of immunology. 44(10):2938-48.

Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection

Jost S, Moreno-Nieves UY, Garcia-Beltran WF, Rands K, Reardon J, Toth I, Piechocka-Trocha A, Altfeld M, Addo MM. Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection. (2013) Retrovirology. 10:74.