The Climate Change Burden on Immune Health: Are Persons Living With HIV More at Risk?

Woolley G, Kroll K, Hoffman K, Ward A, Corneli A, Mudrak SV, Qureshi MU, Okeke NL, Chan C, Jones AD, Tomaras GD, Reeves RK. The Climate Change Burden on Immune Health: Are Persons Living With HIV More at Risk? AIDS Res Hum Retroviruses. 2024 May 16. doi: 10.1089/AID.2024.0050. Epub ahead of print. PMID: 38753709.

Natural killer-like B cells are a distinct but infrequent innate immune cell subset modulated by SIV infection of rhesus macaques

Manickam C, Upadhyay AA, Woolley G, Kroll KW, Terry K, Broedlow CA, Klatt NR, Bosinger SE, Reeves RK. Natural killer-like B cells are a distinct but infrequent innate immune cell subset modulated by SIV infection of rhesus macaques. PLoS Pathog. 2024 May 13;20(5):e1012223. doi: 10.1371/journal.ppat.1012223. PMID: 38739675; PMCID: PMC11115201.

Intersectional climate justice, health equity, and HIV

Wilson SM, Woolley G, Hawn C, Hoffman K, Jones AD, Chan C, Mudrak SV, Qureshi MU, Ward A, Knippler ET, Okeke NL, Corneli A, Tomaras GD, Reeves RK. Intersectional climate justice, health equity, and HIV. Lancet HIV. 2024 May;11(5):e280-e281. doi: 10.1016/S2352-3018(24)00062-6. Epub 2024 Apr 3. PMID: 38582097.

Antigen-specific memory NK cell responses against HIV and influenza use the NKG2/HLA-E axis

Jost S, Lucar O, Lee E, Yoder T, Kroll K, Sugawara S, Smith S, Jones R, Tweet G, Werner A, Tomezsko PJ, Dugan HL, Ghofrani J, Rascle P, Altfeld M, Müller-Trutwin M, Goepfert P, Reeves RK. Antigen-specific memory NK cell responses against HIV and influenza use the NKG2/HLA-E axis. Sci Immunol. 2023 Dec 8;8(90):eadi3974. doi: 10.1126/sciimmunol.adi3974. Epub 2023 Dec 8. PMID: 38064568.

Adaptive MHC-E restricted tissue-resident NK cells are associated with persistent low antigen load in alveolar macrophages after SARS-CoV-2 infection

Huot N, Planchais C, Contreras V, Jacquelin B, Petitdemange C, Lazzerini M, Rosenbaum P, Rey F, Reeves RK, Grand RL, Mouquet H, Müller-Trutwin M. Adaptive MHC-E restricted tissue-resident NK cells are associated with persistent low antigen load in alveolar macrophages after SARS-CoV-2 infection. Nat Immunol 24, 2068–2079 (2023). https://doi.org/10.1038/s41590-023-01661-4

SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells

Huot N, Planchais C, Rosenbaum P, Contreras V, Jacquelin B, Petitdemange C, Lazzerini M, Beaumont E, Orta-Resendiz A, Rey FA, Reeves RK, Le Grand R, Mouquet H, Müller-Trutwin M. SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells. Nat Immunol. 2023 Dec;24(12):2068-2079. doi: 10.1038/s41590-023-01661-4. Epub 2023 Nov 2. PMID: 37919524; PMCID: PMC10681903.

Natural Killer Cells Regulate Acute SIV Replication, Dissemination, and Inflammation, but Do Not Impact Independent Transmission Events

Woolley G, Mosher M, Kroll K, Jones R, Hueber B, Sugawara S, Manickam C, Terry K, Varner V, Lifton M, Ram D, Fennessey CM, Keele BF, Reeves RK. Natural Killer Cells Regulate Acute SIV Replication, Dissemination, and Inflammation, but Do Not Impact Independent Transmission Events. J Virol. 2023 Jan 31;97(1):e0151922. doi: 10.1128/jvi.01519-22. Epub 2022 Dec 13. PMID: 36511699; PMCID: PMC9888193

Physiological and pathological influences

Rascle P, Woolley G, Jost S, Manickam C, Reeves RK. NK cell education: Physiological and pathological influences. Front Immunol. 2023 Jan 20;14:1087155. doi: 10.3389/fimmu.2023.1087155. PMID: 36742337; PMCID: PMC9896005.

Protocol for identification and computational analysis of human natural killer cells using flow cytometry and R. STAR Protoc

Kroll K, Reeves RK. Protocol for identification and computational analysis of human natural killer cells using flow cytometry and R. STAR Protoc. 2023 Jan 19;4(1):102044. doi: 10.1016/j.xpro.2023.102044. Epub ahead of print. PMID: 36853664; PMCID: PMC9871333.

A genetically engineered, stem-cell-derived cellular vaccine

Cooper, A., Sidaway, A., Chandrashekar, A., Latta, E., Chakraborty, K., Yu, J., McMahan, K., Giffin, V., Manickam, C., Kroll, K., Mosher, M., Reeves, R. K., Gam, R., Arthofer, E., Choudhry, M., Henley, T., & Barouch, D. H. (2022). A genetically engineered, stem-cell-derived cellular vaccine. Cell reports. Medicine3(12), 100843. https://doi.org/10.1016/j.xcrm.2022.100843