Neutralization of SARS-CoV-2 Omicron subvariant BA.2.87.1

Lasrado N, Rössler A, Rowe M, Collier AY, Barouch DH. Neutralization of SARS-CoV-2 Omicron subvariant BA.2.87.1. Vaccine. 2024 Apr 2;42(9):2117-2121. doi: 10.1016/j.vaccine.2024.03.007. Epub 2024 Mar 7. PMID: 38458874.

Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer

Alsaiari SK, Nadeef S, Daristotle JL, Rothwell W, Du B, Garcia J, Zhang L, Sarmadi M, Forster TA, Menon N, Lin SQ, Tostanoski LH, Hachmann N, Wang EY, Ventura JD, Barouch DH, Langer R, Jaklenec A. Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer. Sci Adv. 2024 Mar 8;10(10):eadj6380. doi: 10.1126/sciadv.adj6380. Epub 2024 Mar 6. PMID: 38446889; PMCID: PMC10917347.

Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques

Lim SY, Lee J, Osuna CE, Vikhe P, Schalk DR, Chen E, Fray E, Kumar M, Schultz-Darken N, Rakasz E, Capuano S, Ladd RA, Gil HM, Evans DT, Jeng EK, Seaman M, Martin M, Van Dorp C, Perelson AS, Wong HC, Siliciano JD, Siliciano R, Safrit JT, Nixon DF, Soon-Shiong P, Nussenzweig M, Whitney JB. Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques. Science. 2024 Mar 8;383(6687):1104-1111. doi: 10.1126/science.adf7966. Epub 2024 Feb 29. PMID: 38422185; PMCID: PMC11022498.

A VRC13-like bNAb response is associated with complex escape pathways in HIV-1 envelope

Joshi VR, Claiborne DT, Pack ML, Power KA, Newman RM, Batorsky R, Bean DJ, Goroff MS, Lingwood D, Seaman MS, Rosenberg E, Allen TM.2024.A VRC13-like bNAb response is associated with complex escape pathways in HIV-1 envelope. J Virol98:e01720-23.https://doi.org/10.1128/jvi.01720-23

Impact of LS Mutation on Pharmacokinetics of Preventive HIV Broadly Neutralizing Monoclonal Antibodies: A Cross-Protocol Analysis of 16 Clinical Trials in People without HIV

Mayer BT, Zhang L, deCamp AC, Yu C, Sato A, Angier H, Seaton KE, Yates N, Ledgerwood JE, Mayer K, et al. Impact of LS Mutation on Pharmacokinetics of Preventive HIV Broadly Neutralizing Monoclonal Antibodies: A Cross-Protocol Analysis of 16 Clinical Trials in People without HIV. Pharmaceutics. 2024; 16(5):594. https://doi.org/10.3390/pharmaceutics16050594

High Frequency of Prior Severe Acute Respiratory Syndrome Coronavirus 2 Infection by Sensitive Nucleocapsid Assays

Joseph P Nkolola, Jinyan Liu, Ai-ris Y Collier, Catherine Jacob-Dolan, Yasmeen Senussi, Ella Borberg, Zoe Swank, David R Walt, Dan H Barouch, High Frequency of Prior Severe Acute Respiratory Syndrome Coronavirus 2 Infection by Sensitive Nucleocapsid Assays, The Journal of Infectious Diseases, 2024;, jiae174, https://doi.org/10.1093/infdis/jiae174

Neutralization of SARS-CoV-2 Omicron subvariant BA.2.87.1

Lasrado N, Rössler A, Rowe M, Collier AY, Barouch DH. Neutralization of SARS-CoV-2 Omicron subvariant BA.2.87.1. Vaccine. 2024 Apr 2;42(9):2117-2121. doi: 10.1016/j.vaccine.2024.03.007. Epub 2024 Mar 7. PMID: 38458874.

Modeling resistance to the broadly neutralizing antibody PGT121 in people living with HIV-1

Cassidy T, Stephenson KE, Barouch DH, Perelson AS (2024) Modeling resistance to the broadly neutralizing antibody PGT121 in people living with HIV-1. PLOS Computational Biology 20(3): e1011518. https://doi.org/10.1371/journal.pcbi.1011518

PANINI: Combined protein and nucleic acid imaging in tissues

Jiang, S. PANINI: Combined protein and nucleic acid imaging in tissues. Nat Rev Immunol (2024). https://doi.org/10.1038/s41577-024-01028-2

Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques

Jacob-Dolan C, Ty D, Hope D, McMahan K, Liu J, Powers OC, Cotter CA, Sciacca M, Wu C, Borducchi E, Bouffard E, Richter H, Velasco J, Teow E, Boursiquot M, Cook A, Feliciano K, Yalley-Ogunro J, Seaman MS, Pessiant L, Lewis MG, Andersen H, Moss B, Barouch DH. Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques. Sci Transl Med. 2024 Mar 27;16(740):eadl4317. doi: 10.1126/scitranslmed.adl4317. Epub 2024 Mar 27. PMID: 38536937.