Mining the CD4 antigen repertoire for next-generation tuberculosis vaccines

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Vidal SJ, Lasrado N, Tostanoski LH, Chaudhari J, Mbiwan ER, Neka GD, Strutton EA, Espinosa Perez AA, Sellers D, Barrett J, Lifton M, Wakabayashi S, Eshaghi B, Borducchi EN, Aid M, Li W, Scriba TJ, Jaklenec A, Langer R, Barouch DH. Mining the CD4 antigen repertoire for next-generation tuberculosis vaccines. Cell. 2025 Nov 26;188(24):6791-6803.e13. doi: 10.1016/j.cell.2025.08.027. Epub 2025 Sep 15. PMID: 40957415; PMCID: PMC12445596.

Myeloid cell recruitment and activation through systemic and mucosae-directed cytokine therapy

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Manickam C, Jones R, Deb Adhikary NR, Kroll KW, Terry K, Balachandran H, Woolley G, Tomaras GD, Villinger FJ, Reeves RK. Myeloid cell recruitment and activation through systemic and mucosae-directed cytokine therapy. Immunol Cell Biol. 2025 Nov-Dec;103(10):945-956. doi: 10.1111/imcb.70061. Epub 2025 Oct 7. PMID: 41054306; PMCID: PMC12667110.

Building a better natural killer (NK) cell: Fc receptor engineering strategies for NK cell therapeutics

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Kroll KW, Woolley G, Reeves RK. Building a better natural killer (NK) cell: Fc receptor engineering strategies for NK cell therapeutics. Future Virol. 2025 Oct;20(10):369-371. doi: 10.1080/17460794.2025.2580187. Epub 2025 Oct 29. PMID: 41409329; PMCID: PMC12707376.

Epstein–Barr virus exploits desmocollin 2 as the principal epithelial cell entry receptor

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Wang H, Mou Z, Yeo YY, Ge Q, Liu X, Narita Y, Li Z, Wang C, Li W, Zhao KR, Li J, Bu W, Gewurz B, Cohen JI, Teng M, Dai X, Liu X, Jiang S, Zhao B. Epstein-Barr virus exploits desmocollin 2 as the principal epithelial cell entry receptor. Nat Microbiol. 2025 Nov;10(11):2781-2796. doi: 10.1038/s41564-025-02126-0. Epub 2025 Sep 26. PMID: 41006833.

Immunopathogenesis of lethal H5N1 avian influenza virus clade 2.3.4.4b infection in macaques

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Andersen H, Aid M, Stone JJ, Lyons CE, Berlied A, Nkolola J, Lasrado N, Peterson M, Pessaint L, Kitajewski C, Yalley-Ogunro J, Porto M, Stone R, Cabus M, Valentin D, Van Ry A, Narvaez B, Orekov T, Kar S, Teow E, Kouneski K, Ferreira A, Velasco J, Campbell R, Henderson C, Beah W, Patel G, Finneyfrock B, Cook A, Paul S, Haasnoot J, Ramirez-Carvajal L, Koldijk MH, Arias Rivas S, Koch CM, Goudsmit J, Lewis MG, Martinot AJ, Barouch DH. Immunopathogenesis of lethal H5N1 avian influenza virus clade 2.3.4.4b infection in macaques. Immunity. 2025 Sep 9;58(9):2157-2165.e5. doi: 10.1016/j.immuni.2025.07.020. Epub 2025 Aug 18. PMID: 40829590.

A Novel Approach for Preventing Respiratory Virus Infections

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Vidal SJ, Barouch DH. A Novel Approach for Preventing Respiratory Virus Infections. JAMA Intern Med. 2025;185(11):1317–1318. doi:10.1001/jamainternmed.2025.4297

Association of Glucagon-Like Peptide-1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

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Lu Y, Dai H, Tang H, Donahoo WT, George TJ, Sun RC, Jiang S, Tan AC, Guo Y, Licht JD, Allen JM, Lee KP, Guo J, Bian J. Association of Glucagon-Like Peptide-1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes. Obesity (Silver Spring). 2025 Aug 21. doi: 10.1002/oby.24366.

Corrigendum to ‘Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study’. EBioMedicine 2024;108: 105320

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Kenny A, van Duijn J, Dintwe O, Heptinstall J, Burnham R, Sawant S, Zhang L, Mielke D, Khuzwayo S, Omar FL, Stanfield-Oakley S, Keyes T, Dunn B, Goodman D, Fong Y, Benkeser D, Zou R, Hural J, Hyrien O, Juraska M, Luedtke A, van der Laan L, Giorgi EE, Magaret C, Carpp LN, Pattacini L, van de Kerkhof T, Korber B, Willems W, Fisher LH, Schuitemaker H, Swann E, Kublin JG, Pau MG, Buchbinder S, Tomaka F, Nijs S, Lavreys L, Gelderblom HC, Corey L, Mngadi K, Gray GE, Borducchi E, Hendriks J, Seaton KE, Zolla-Pazner S, Barouch DH, Ferrari G, De Rosa SC, McElrath MJ, Andersen-Nissen E, Stieh DJ, Tomaras GD, Gilbert PB; Imbokodo Study and Correlates Group. Corrigendum to ‘Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study’. EBioMedicine 2024;108: 105320. EBioMedicine. 2025 Sep;119:105874. doi: 10.1016/j.ebiom.2025.105874. Epub 2025 Aug 23. Erratum for: EBioMedicine. 2024 Oct;108:105320. doi: 10.1016/j.ebiom.2024.105320. PMID: 40850015; PMCID: PMC12789700.

Elevated peripheral and nervous system inflammation is associated with decreased short-chain fatty acid levels in Zika virus-infected macaques

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Schroeder TA, Manuzak JA, Miller CJ, Gustin AT, Basting CM, Cheu RK, Velez A, Driscoll CB, Tisoncik-Go J, Schifanella L, Hensley-McBain T, Evandy CA, Smith EA, Bratt D, Shields-Cutler R, Smedley J, Fuller DH, Barouch DH, O’Connor MA, Gale M, Klatt NR.2025.Elevated peripheral and nervous system inflammation is associated with decreased short-chain fatty acid levels in Zika virus-infected macaques. J Virol99:e01003-25.https://doi.org/10.1128/jvi.01003-25

Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies

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Ryan S. Roark, Rumi Habib, Jason Gorman, Hui Li, Andrew Jesse Connell, Mattia Bonsignori, Yicheng Guo, Michael P. Hogarty, Adam S. Olia, Kirsten J. Sowers, Baoshan Zhang, Frederic Bibollet-Ruche, Tatsiana Bylund, Sean Callaghan, John W. Carey, Gabriele Cerutti, Darcy R. Harris, Wanting He, Emily Lewis, Tracy Liu, Rosemarie D. Mason, Yujie Qiao, Younghoon Park, Juliette M. Rando, Ajay Singh, Jeremy J. Wolff, Q. Paula Lei, Mark K. Louder, Raiees Andrabi, Nicole A. Doria-Rose, Kevin O. Saunders, Michael S. Seaman, Barton F. Haynes, Daniel W. Kulp, John R. Mascola, Mario Roederer, Theodore C. Pierson, Zizhang Sheng, Beatrice H. Hahn, George M. Shaw, Peter D. Kwong, Lawrence Shapiro; Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies. J Exp Med 6 October 2025; 222 (10): e20250638. doi: https://doi.org/10.1084/jem.20250638