Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.

Chamcha V, Reddy PBJ, Kannanganat S, Wilkins C, Gangadhara S, Velu V, Green R, Law GL, Chang J, Bowen JR, Kozlowski PA, Lifton M, Santra S, Legere T, Chea LS, Chennareddi L, Yu T, Suthar MS, Silvestri G, Derdeyn CA, Gale M Jr, Villinger F, Hunter E, Amara RR. Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy. 2019. Sci Trans Med. 11:519.

A meta-analysis of passive immunization studies shows that serum-neutralizing antibody titer associates with protection against SHIV challenge.

Pegu A, Borate B, Huang Y, Pauthner MG, Hessell AJ, Julg B, Doria-Rose NA, Schmidt SD, Carpp LN, Cully MD, Chen X, Shaw GM, Barouch DH, Haigwood NL, Corey L, Burton DR, Roederer M, Gilbert PB, Mascola JR, Huang Y. A meta-analysis of passive immunization studies shows that serum-neutralizing antibody titer associates with protection against SHIV challenge. Cell Host Microbe 2019; 26:336-346.

Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.

Escolano A, Gristick HB, Abernathy ME, Merkenschlager J, Gautam R, Oliveira TY, Pai J, West AP Jr, Barnes CO, Cohen AA, Wang H, Golijanin J, Yost D, Keeffe JR, Wang Z, Zhao P, Yao KH, Bauer J, Nogueira L, Gao H, Voll AV, Montefiori DC, Seaman MS, Gazumyan A, Silva M, McGuire AT, Stamatatos L, Irvine DJ, Wells L, Martin MA, Bjorkman PJ, Nussenzweig MC. Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature. 2019 Jun;570(7762):468-473.

Survey of BK virus screening practices by American Society of Transplantation members.

Tan CS, Gabardi S, Pavlakis M, Survey of BK virus screening practices by American Society of Transplantation members. Clin Transplant; 2019 (In Press) PMID 31152561

A microbial expression system for high-level production of scFv HIV-neutralizing antibody fragments in Escherichia coli.

Petrus MLC, Kiefer LA, Puri P, Heemskerk E, Seaman MS, Barouch DH, Arias S, van Wezel GP, Havenga M. A microbial expression system for high-level production of scFv HIV-neutralizing antibody fragments in Escherichia coli. Appl. Microbiol. Biotechnol. 2019; in press.

Impact of CMV Infection on Natural Killer Cell Clonal Repertoire in CMV-Naïve Rhesus Macaques.

Truitt, L. L., Yang, D., Espinoza, D. A., Fan, X., Ram, D. R., Moström, M. J., … Wu, C. (2019). Impact of CMV Infection on Natural Killer Cell Clonal Repertoire in CMV-Naïve Rhesus Macaques. Frontiers in immunology, 10, 2381. doi:10.3389/fimmu.2019.02381

A natural impact: NK cells at the intersection of cancer and HIV disease.

Lucar, O., Reeves, R.K., and Jost, S. 2019 A natural impact: NK cells at the intersection of cancer and HIV disease. Front. Immunol. 10:1850. PMID: 31474977. PMCID: PMC6705184

Knowns and unknowns of assaying antibody-dependent cell-mediated cytotoxicity against HIV-1. 2019.

Lewis, G., Ackerman, M.E., Scarlatti, G, Moog, C, Robert-Guroff, M., Kent, S.J., Overbaugh, J., Reeves, R.K., Ferrari, G., and Thyagarajan, B. Knowns and unknowns of assaying antibody-dependent cell-mediated cytotoxicity against HIV-1. 2019. Front. Immunol. 10:1025. PMID: 31134085. PMCID: PMC6522882

A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials.

Ehrenberg PK, Shangguan S, Issac B, Alter G, Geretz A, Izumi T, Bryant C, Eller MA, Wegmann F, Apps R, Creegan M, Bolton DL, Sekaly RP, Robb ML, Gramzinski RA, Pau MG, Schuitemaker H, Barouch DH, Michael NL, Thomas R. A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials. Sci. Transl. Med. 2019; 11: eaaw4236.

Lack of therapeutic efficacy of an antibody to α4β7 in SIVmac251-infected rhesus macaques.

Abbink P, Mercado NB, Nkolola JP, Peterson RL, Tuyishime H, McMahan K, Moseley ET, Borducchi EN, Chandrashekar A, Bondzie EA, Agarwal A, Belli AJ, Reimann KA, Keele BF, Geleziunas R, Lewis MG, Barouch DH. Lack of therapeutic efficacy of an antibody to α4β7 in SIVmac251-infected rhesus macaques. Science 2019; 365:1029-1033.