Harvard HIV and aging workshop: Perspective and priorities from Claude D. Pepper Centers and Centers for AIDS Research.

Montano, M., Bhasin, S., D’Aquila, R.T., Erlandson, K.M., Evans, W.J., Funderburg, N.T., Justice, A., Ndhlovu, L., Ojikutu, B., Pahor, M., Pahwa, S., Ryan, A.S., Schrack, J., Schultz, M.B., Sebatiani, P, Sinclair, D., Tripp, J., Walker, B., Womack, J.A., Yung, R., and Reeves, R.K. Harvard HIV and aging workshop: Perspective and priorities from Claude D. Pepper Centers and Centers for AIDS Research. AIDS Research and Human Retroviruses Epub. doi: 10.1089/AID.2019.0130. PMID: 31456412

Safety, pharmacokinetics, and immunogenicity of the combination of the broadly neutralizing anti-HIV-1 antibodies 3BNC117 and 10-1074 in healthy adults: A randomized, phase 1 study.

Cohen YZ, Butler AL, Millard K, Witmer-Pack M, Levin R, et al. (2019) Safety, pharmacokinetics, and immunogenicity of the combination of the broadly neutralizing anti-HIV-1 antibodies 3BNC117 and 10-1074 in healthy adults: A randomized, phase 1 study. PLOS ONE 14(8): e0219142.

HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors.

Koneru PC, Francis AC, Deng N, Rebensburg SV, Hoyte AC, Lindenberger J, Adu-Ampratwum D, Larue RC, Wempe MF, Engelman AN, Lyumkis D, Fuchs JR, Levy RM, Melikyan GB, Kvaratskhelia M. HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors. Elife 2019 May 23;8. pii: e46344. doi: 10.7554/eLife.46344. PubMed PMID: 31120420; PubMed Central PMCID: PMC6581505.

Semaphorin 7A modulates cytokine-induced memory-like responses by human natural killer cells.

Ghofrani J, Lucar O, Dugan H, Reeves RK, Jost S. Semaphorin 7A modulates cytokine-induced memory-like responses by human natural killer cells. (2019) European Journal of Immunology. 49(8):1153-1166.

A Highly Unusual V1 Region of Env in an Elite Controller of HIV Infection.

Silver ZA, Dickinson GM, Seaman MS, Desrosiers RC. A Highly Unusual V1 Region of Env in an Elite Controller of HIV Infection. J Virol. 2019 May 15;93(10). doi: 10.1128/JVI.00094-19.

HIV-1 neutralizing antibody signatures and application to epitope-targeted vaccine design.

Bricault CA, Yusim K, Seaman MS, Yoon H, Theiler J, Giorgi EE, Wagh K, Theiler M, Hraber P, Macke JP, Kreider EF, Learn GH, Hahn BH, Scheid JF, Kovacs JM, Shields JL, Lavine CL, Ghantous F, Rist M, Bayne MG, Neubauer GH, McMahan K, Peng H, Chéneau C, Jones JJ, Zeng J, Ochsenbauer C, Nkolola JP, Stephenson KE, Chen B, Gnanakaran S, Bonsignori M, Williams LD, Haynes BF, Doria-Rose N, Mascola JR, Montefiori DC, Barouch DH*, Korber B*. HIV-1 neutralizing antibody signatures and application to epitope-targeted vaccine design. Cell Host Microbe 2019; 25:59-72.

SIV infection modulates CD94(KLRD1)+ NK cells in rhesus macaques.

Ram DR, Lucar O, Hueber B, Reeves RK. 2019. SIV infection modulates CD94(KLRD1)+ NK cells in rhesus macaques. J. Virol. 93(16):e00731-19. PMID:31167916. PMCID: PMC6675877

A HTRF based competitive binding assay for screening specific inhibitors of HIV-1 capsid assembly targeting the C-terminal domain of capsid.

Zhang DW, Luo RH, Xu L, Yang L-M, Xu X-S, Bedwell GJ, Engelman AN, Zheng Y-T, Chang S. A HTRF based competitive binding assay for screening specific inhibitors of HIV-1 capsid assembly targeting the C-terminal domain of capsid. Antiviral Res 2019 Sep;169:104544. doi: 10.1016/j.antiviral.2019.104544. Epub 2019 Jun 27. PubMed PMID: 31254557.

HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells.

Hartweger H, McGuire AT, Horning M, Taylor JJ, Dosenovic P, Yost D, Gazumyan A, Seaman MS, Stamatatos L, Jankovic M, Nussenzweig MC. HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells. J Exp Med. 2019 Jun 3;216(6):1301-1310.

Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.

Chamcha V, Reddy PBJ, Kannanganat S, Wilkins C, Gangadhara S, Velu V, Green R, Law GL, Chang J, Bowen JR, Kozlowski PA, Lifton M, Santra S, Legere T, Chea LS, Chennareddi L, Yu T, Suthar MS, Silvestri G, Derdeyn CA, Gale M Jr, Villinger F, Hunter E, Amara RR. Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy. 2019. Sci Trans Med. 11:519.