The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase.

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Slaughter A, Jurado KA, Deng N, Feng L, Kessl JJ, Shkriabai N, Larue RC, Fadel HJ, Patel PA, Jena N, Fuchs JR, Poeschla E, Levy RM, Engelman A, Kvaratskhelia M. The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase. Retrovirology 2014 Nov 25;11:100. doi: 10.1186/s12977-014-0100-1. PubMed PMID: 25421939; PubMed Central PMCID: PMC4251946.

Characterization and immunogenicity of a novel mosaic M HIV-1 gp140 trimer.

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Nkolola JP, Bricault CA, Cheung A, Shields J, Perry J, Kovacs JM, Giorgi E, van Winsen M, Apetri A, Brinkman-van der Linden EC, Chen B, Korber B, Seaman MS, Barouch DH. Characterization and immunogenicity of a novel mosaic M HIV-1 gp140 trimer. J. Virol. 2014; 88:9538-9532.

Host and viral determinants for MxB restriction of HIV-1 infection.

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Matreyek KA, Wang W, Serrao E, Singh PK, Levin HL, Engelman A. Host and viral determinants for MxB restriction of HIV-1 infection. Retrovirology 2014 Oct 25;11:90. doi: 10.1186/s12977-014-0090-z. PubMed PMID: 25348155; PubMed Central PMCID: PMC4213484.

Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice.

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Halper-Stromberg A, Lu CL, Klein F, Horwitz JA, Bournazos S, Nogueira L, Eisenreich TR, Liu C, Gazumyan A, Schaefer U, Furze RC, Seaman MS, Prinjha R, Tarakhovsky A, Ravetch JV, Nussenzweig MC. Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice. Cell. 2014, 158(5):989-99.

The polyomavirus puzzle: is host immune response beneficial in controlling BK virus after adult hematopoietic cell transplantion?

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Satyanarayana G, Marty FM, Tan CS. 2014. The polyomavirus puzzle: is host immune response beneficial in controlling BK virus after adult hematopoietic cell transplantion? Transplant Infectious Disease, 2014; 16: 521-31.

Common features of mucosal and peripheral antibody responses elicited by candidate HIV-1 vaccines in rhesus monkeys.

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Li H, Stephenson KE, Kang ZH, Lavine CL, Seaman MS, Barouch DH. Common features of mucosal and peripheral antibody responses elicited by candidate HIV-1 vaccines in rhesus monkeys. J. Virol. 2014; 88:13510-13515.

Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection.

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Li, H., Evans, T. I., Gillis, J., Estes, J.D., Keele, B.F., Klatt, N.R., and Reeves, R. K. 2014. Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection. PLoS Path. 10(12):e1004551. PMID: 25503264. PMCID: 4263758

NK cell responses to simian immunodeficiency virus vaginal exposure in naive and vaccinated rhesus macaques.

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Shang, L., Smith, A., Duan, L., Perkey, K. E., Lucy, Q. Wietgrefe, S., Zupanic, M., Southern, P. J., Reeves, R. K., Johnson, R. P., and Haase, A. T. 2014. NK cell responses to simian immunodeficiency virus vaginal exposure in naive and vaccinated rhesus macaques. J. Immunol. 193(1):277-84. PMID: 24899503. PMCID: PMC4083479

Toll-like receptor 7/8 (TLR7/8) and TLR9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques.

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Moody MA, Santra S, Vandergrift NA, Sutherland LL, Gurley TC, Drinker MS, Allen AA, Xia SM, Meyerhoff RR, Parks R, Lloyd KE, Easterhoff D, Alam SM, Liao HX, Ward BM, Ferrari G, Montefiori DC, Tomaras GD, Seder RA, Letvin NL, Haynes BF. Toll-like receptor 7/8 (TLR7/8) and TLR9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques. J. Virol. 2014; 88:3329-3339

Comparison of multiple adjuvants on the stability and immunogenicity of a clade C HIV-1 gp140 trimer.

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Nkolola JP, Cheung A, Perry JR, Carter D, Reed S, Schuitemaker H, Pau MG, Seaman MS, Chen B, Barouch DH. Comparison of multiple adjuvants on the stability and immunogenicity of a clade C HIV-1 gp140 trimer. Vaccine 2014; 32:2109-2116.