Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site

Caniels TG, Medina-Ramìrez M, Zhang S, Kratochvil S, Xian Y, Koo JH, Derking R, Samsel J, van Schooten J, Pecetta S, Lamperti E, Yuan M, Carrasco MR, Del Moral Sánchez I, Allen JD, Bouhuijs JH, Yasmeen A, Ketas TJ, Snitselaar JL, Bijl TPL, Martin IC, Torres JL, Cupo A, Shirreff L, Rogers K, Mason RD, Roederer M, Greene KM, Gao H, Silva CM, Baken IJL, Tian M, Alt FW, Pulendran B, Seaman MS, Crispin M, van Gils MJ, Montefiori DC, McDermott AB, Villinger FJ, Koup RA, Moore JP, Klasse PJ, Ozorowski G, Batista FD, Wilson IA, Ward AB, Sanders RW. Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site. Sci Immunol. 2024 Aug 30;9(98):eadk9550. doi: 10.1126/sciimmunol.adk9550. Epub 2024 Aug 30. PMID: 39213338.

FcαRI (CD89) is upregulated on subsets of mucosal and circulating NK cells and regulates IgA-class specific signaling and functions

Kroll KW, Hueber B, Balachandran H, Afifi A, Manickam C, Nettere D, Pollara J, Hudson A, Woolley G, Ndhlovu LC, Reeves RK. FcαRI (CD89) is upregulated on subsets of mucosal and circulating NK cells and regulates IgA-class specific signaling and functions. Mucosal Immunol. 2024 Aug;17(4):692-699. doi: 10.1016/j.mucimm.2024.04.003. Epub 2024 Apr 25. PMID: 38677592; PMCID: PMC11323182.

Graph Fourier transform for spatial omics representation and analyses of complex organs

Chang, Y., Liu, J., Jiang, Y., Ma, A., Yeo, Y. Y., Guo, Q., McNutt, M., Krull, J. E., Rodig, S. J., Barouch, D. H., Nolan, G. P., Xu, D., Jiang, S., Li, Z., Liu, B., & Ma, Q. (2024). Graph Fourier transform for spatial omics representation and analyses of complex organs. Nature communications15(1), 7467. https://doi.org/10.1038/s41467-024-51590-5

Ad26.M.Env ZIKV vaccine protects pregnant rhesus macaques and fetuses against Zika virus infection

Martinot, A. J., Cox, F., Abbink, P., Hecht, J. L., Bronson, R., Borducchi, E. N., Rinaldi, W. J., Ferguson, M. J., De La Barrera, R. A., Zahn, R., van der Fits, L., & Barouch, D. H. (2024). Ad26.M.Env ZIKV vaccine protects pregnant rhesus macaques and fetuses against Zika virus infection. NPJ vaccines9(1), 157. https://doi.org/10.1038/s41541-024-00927-8

Patterns and predictors of COVID-19 vaccination among young adults at 44 US sites: Secondary analysis of a randomized, controlled, open-label trial, March – December 2021

Vielot, N. A., Kelly, N. K., Ludema, C., Rosenberg, M., Brown, E. R., Janes, H. E., Kublin, J. G., Stephenson, K. E., Marcelin, J. R., & Pettifor, A. (2024). Patterns and predictors of COVID-19 vaccination among young adults at 44 US sites: Secondary analysis of a randomized, controlled, open-label trial, March – December 2021. Vaccine42(23), 126237. https://doi.org/10.1016/j.vaccine.2024.126237

NK cells modulate in vivo control of SARS-CoV-2 replication and suppression of lung damage

Balachandran H, Kroll K, Terry K, Manickam C, Jones R, Woolley G, Hayes T, Martinot AJ, Sharma A, Lewis M, Jost S, Reeves RK. NK cells modulate in vivo control of SARS-CoV-2 replication and suppression of lung damage. PLoS Pathog. 2024 Aug 12;20(8):e1012439. doi: 10.1371/journal.ppat.1012439. PMID: 39133756; PMCID: PMC11341101.

NK cells modulate in vivo control of SARS-CoV-2 replication and suppression of lung damage

Balachandran, H., Kroll, K., Terry, K., Manickam, C., Jones, R., Woolley, G., Hayes, T., Martinot, A. J., Sharma, A., Lewis, M., Jost, S., & Reeves, R. K. (2024). NK cells modulate in vivo control of SARS-CoV-2 replication and suppression of lung damage. PLoS pathogens20(8), e1012439. https://doi.org/10.1371/journal.ppat.1012439

Knockdowns of CD3zeta Chain in Primary NK Cells Illustrate Modulation of Antibody-Dependent Cellular Cytotoxicity Against Human Immunodeficiency Virus-1

Sugawara, S., Lee, E., Craemer, M. A., Pruitt, A., Balachandran, H., Gressens, S. B., Kroll, K., Manickam, C., Li, Y., Jost, S., Woolley, G., & Reeves, R. K. (2024). Knockdowns of CD3zeta Chain in Primary NK Cells Illustrate Modulation of Antibody-Dependent Cellular Cytotoxicity Against Human Immunodeficiency Virus-1. AIDS research and human retroviruses, 10.1089/AID.2023.0114. Advance online publication. https://doi.org/10.1089/AID.2023.0114

Prediction of differential Gag versus Env responses to a mosaic HIV-1 vaccine regimen by HLA class I alleles

Nelson GW, van Duijn J, Yuki Y, Pau MG, Tomaka F, Lavreys L, DeRosa SC, McElrath MJ, Kirk GD, Michael NL, Haas DW, Deeks SG, Wolinsky S, Walker B, Barouch DH, Stieh D, Carrington M.2024.Prediction of differential Gag versus Env responses to a mosaic HIV-1 vaccine regimen by HLA class I alleles. J Virol98:e00281-24.https://doi.org/10.1128/jvi.00281-24

Prediction of differential Gag versus Env responses to a mosaic HIV-1 vaccine regimen by HLA class I alleles

Nelson GW, van Duijn J, Yuki Y, Pau MG, Tomaka F, Lavreys L, DeRosa SC, McElrath MJ, Kirk GD, Michael NL, Haas DW, Deeks SG, Wolinsky S, Walker B, Barouch DH, Stieh D, Carrington M.2024.Prediction of differential Gag versus Env responses to a mosaic HIV-1 vaccine regimen by HLA class I alleles. J Virol98:e00281-24.https://doi.org/10.1128/jvi.00281-24