Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study

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Kenny, A., van Duijn, J., Dintwe, O., Heptinstall, J., Burnham, R., Sawant, S., Zhang, L., Mielke, D., Khuzwayo, S., Omar, F. L., Stanfield-Oakley, S., Keyes, T., Dunn, B., Goodman, D., Fong, Y., Benkeser, D., Zou, R., Hural, J., Hyrien, O., Juraska, M., … Imbokodo Study and Correlates Group (2024). Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study. EBioMedicine, 108, 105320. https://doi.org/10.1016/j.ebiom.2024.105320

Mosaic HIV-1 vaccine and SHIV challenge strain V2 loop sequence identity and protection in primates

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Vanshylla, K., Tolboom, J., Stephenson, K. E., Feddes-de Boer, K., Verwilligen, A., Rosendahl Huber, S. K., Rutten, L., Schuitemaker, H., Zahn, R. C., Barouch, D. H., & Wegmann, F. (2024). Mosaic HIV-1 vaccine and SHIV challenge strain V2 loop sequence identity and protection in primates. NPJ vaccines, 9(1), 179. https://doi.org/10.1038/s41541-024-00974-1

Compartment-specific antibody correlates of protection to SARS-CoV-2 Omicron in macaques

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Tong X, Wang Q, Jung W, Chicz TM, Blanc R, Parker LJ, Barouch DH, McNamara RP. Compartment-specific antibody correlates of protection to SARS-CoV-2 Omicron in macaques. iScience. 2024 Jun 4;27(9):110174. doi: 10.1016/j.isci.2024.110174. PMID: 39224511; PMCID: PMC11367469.

Mpox infection of stromal cells and macrophages of macaque with endometriosis

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Hall, J. M., Lyons, C. E., Li, J., Martinez-Romero, G., Hayes, T., Cook, A., Barouch, D. H., & Martinot, A. J. (2024). Mpox infection of stromal cells and macrophages of macaque with endometriosis. Scientific reports, 14(1), 21947. https://doi.org/10.1038/s41598-024-73012-8

High Frequency of Prior Severe Acute Respiratory Syndrome Coronavirus 2 Infection by Sensitive Nucleocapsid Assays

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Joseph P Nkolola, Jinyan Liu, Ai-ris Y Collier, Catherine Jacob-Dolan, Yasmeen Senussi, Ella Borberg, Zoe Swank, David R Walt, Dan H Barouch, High Frequency of Prior Severe Acute Respiratory Syndrome Coronavirus 2 Infection by Sensitive Nucleocapsid Assays, The Journal of Infectious Diseases, Volume 230, Issue 3, 15 September 2024, Pages e601–e604, https://doi.org/10.1093/infdis/jiae174

HIV Vaccine Development at a Crossroads: New B and T Cell Approaches

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Govindan, R., & Stephenson, K. E. (2024). HIV Vaccine Development at a Crossroads: New B and T Cell Approaches. Vaccines, 12(9), 1043. https://doi.org/10.3390/vaccines12091043

Safety and antiviral effect of a triple combination of HIV-1 broadly neutralizing antibodies: a phase 1/2a trial

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Julg B, Walker-Sperling VEK, Wagh K, Aid M, Stephenson KE, Zash R, Liu J, Nkolola JP, Hoyt A, Castro M, Serebryannyy L, Yanosick K, Speidel T, Borducchi EN, Murzda T, Maxfield L, Arduino R, McDermott AB, Gama L, Giorgi EE, Koup RA, Seaman MS, Rolle CP, DeJesus E, Li W, Korber B, Barouch DH. Safety and antiviral effect of a triple combination of HIV-1 broadly neutralizing antibodies: a phase 1/2a trial. Nat Med. 2024 Sep 12. doi: 10.1038/s41591-024-03247-5. Epub ahead of print. PMID: 39266747.

HIV-1 usurps mixed-charge domain-dependent CPSF6 phase separation for higher-order capsid binding, nuclear entry and viral DNA integration

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Sooin Jang, Gregory J Bedwell, Satya P Singh, Hyun Jae Yu, Bjarki Arnarson, Parmit K Singh, Rajalingam Radhakrishnan, AidanDarian W Douglas, Zachary M Ingram, Christian Freniere, Onno Akkermans, Stefan G Sarafianos, Zandrea Ambrose, Yong Xiong, Praju V Anekal, Paula Montero Llopis, Vineet N KewalRamani, Ashwanth C Francis, Alan N Engelman, HIV-1 usurps mixed-charge domain-dependent CPSF6 phase separation for higher-order capsid binding, nuclear entry and viral DNA integration, Nucleic Acids Research, 2024;, gkae769, https://doi.org/10.1093/nar/gkae769

Insights from an observational translational research program during the COVID-19 pandemic: Four years of experience

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Rowe M, Collier AY, Barouch DH. Insights from an observational translational research program during the COVID-19 pandemic: Four years of experience. Vaccine. 2024 Oct 24;42(24):126306. doi: 10.1016/j.vaccine.2024.126306. Epub 2024 Sep 5. PMID: 39241351; PMCID: PMC11401756.

Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study

/in

Kenny A, van Duijn J, Dintwe O, Heptinstall J, Burnham R, Sawant S, Zhang L, Mielke D, Khuzwayo S, Omar FL, Stanfield-Oakley S, Keyes T, Dunn B, Goodman D, Fong Y, Benkeser D, Zou R, Hural J, Hyrien O, Juraska M, Luedtke A, van der Laan L, Giorgi EE, Magaret C, Carpp LN, Pattacini L, van de Kerkhof T, Korber B, Willems W, Fisher LH, Schuitemaker H, Swann E, Kublin JG, Pau MG, Buchbinder S, Tomaka F, Nijs S, Lavreys L, Gelderblom HC, Corey L, Mngadi K, Gray GE, Borducchi E, Hendriks J, Seaton KE, Zolla-Pazner S, Barouch DH, Ferrari G, De Rosa SC, McElrath MJ, Andersen-Nissen E, Stieh DJ, Tomaras GD, Gilbert PB; Imbokodo Study and Correlates Group. Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study. EBioMedicine. 2024 Sep 4;108:105320. doi: 10.1016/j.ebiom.2024.105320. Epub ahead of print. PMID: 39236556.