Quantification of the epitope diversity of HIV-1-specific binding antibodies by peptide microarrays for global HIV-1 vaccine development.

Stephenson KE, Neubauer GH, Reimer U, Pawlowski N, Knaute T, Zerweck J, Korber BT, Barouch DH. Quantification of the epitope diversity of HIV-1-specific binding antibodies by peptide microarrays for global HIV-1 vaccine development. J. Immunol. Methods 2015; 416:105-123.

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.

Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES Jr, Fellinger CH, Joshi VR, Fuchs SP, Martinez-Navio JM, Quinlan BD, Yao AY, Mouquet H, Gorman J, Zhang B, Poignard P, Nussenzweig MC, Burton DR, Kwong PD, Piatak M Jr, Lifson JD, Gao G, Desrosiers RC, Evans DT, Hahn BH, Ploss A, Cannon PM, Seaman MS, Farzan M. AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges. Nature. 2015, 519(7541):87-91.

Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL.

Kumar R, Pan R, Upadhyay C, Mayr L, Cohen S, Wang XH, Balasubramanian P, Nádas A, Seaman MS, Zolla-Pazner S, Gorny MK, Kong XP, Hioe CE. Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL. J. Virol. 2015, 89(17):9090-102.

Sites of retroviral DNA integration: From basic research to clinical applications.

Serrao E, Engelman AN. Sites of retroviral DNA integration: From basic research to clinical applications. Crit Rev Biochem Mol Biol 2016;51(1):26-42. doi: 10.3109/10409238.2015.1102859. Epub 2015 Oct 28. PubMed PMID: 26508664; PubMed Central PMCID: PMC4866806.

Accumulation of Cytotoxic CD16+ NK Cells in Simian Immunodeficiency Virus-infected Lymph Nodes Associated with in Situ Differentiation and Functional Anergy.

Schafer, J. L., Li, H., Evans, T. I., Estes, J. D., and Reeves, R. K. 2015. Accumulation of Cytotoxic CD16+ NK Cells in Simian Immunodeficiency Virus-infected Lymph Nodes Associated with in Situ Differentiation and Functional Anergy. J. Virol. 89(13):6887-6894. PMID: 25903330. PMCID: PMC4468491

Glycan-Dependent Neutralizing Antibodies Are Frequently Elicited in Individuals Chronically Infected with HIV-1 Clade B or C.

Cohen YZ, Lavine CL, Miller CA, Garrity J, Carey BR, Seaman MS. Glycan-Dependent Neutralizing Antibodies Are Frequently Elicited in Individuals Chronically Infected with HIV-1 Clade B or C. AIDS Res. Hum. Retroviruses. 2015, 31(11):1192-201.

Structural basis for retroviral integration into nucleosomes.

Maskell DP, Renault L, Serrao E, Lesbats P, Matadeen R, Hare S, Lindemann D, Engelman AN, Costa A, Cherepanov P. Structural basis for retroviral integration into nucleosomes. Nature 2015 Jul 16;523(7560):366-9. doi: 10.1038/nature14495. Epub 2015 Jun 10. PubMed PMID: 26061770; PubMed Central PMCID: PMC4530500.

Antigen-specific NK cell memory in rhesus macaques.

Reeves RK, Li H, Jost S, Blass E, Li H, Schafer JL, Varner V, Manickam C, Eslamizar L, Altfeld M, Von Andrian UH, Barouch DH. Antigen-specific NK cell memory in rhesus macaques. Nat. Immunol. 2015; 16:927-932.

HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.

Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L, Arendt H, Kim HJ, Lee JH, Pugach P, Williams M, Debnath G, Moldt B, van Breemen MJ, Isik G, Medina-Ramírez M, Back JW, Koff WC, Julien JP, Rakasz EG, Seaman MS, Guttman M, Lee KK, Klasse PJ, LaBranche C, Schief WR, Wilson IA, Overbaugh J, Burton DR, Ward AB, Montefiori DC, Dean H, Moore JP. HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers. Science. 2015, 349(6244):aac4223.

Targeting the gastrointestinal tract to develop novel therapies for HIV.

Reeves, R.K., Burgener, A, and Klatt, N.R. 2015. Targeting the gastrointestinal tract to develop novel therapies for HIV. Clin. Pharmacol. Ther. 98(4):381-386. PMID: 26179624