Human immunodeficiency virus type 1 (HIV-1) capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection.

/in

Ambrose Z, Lee K, Ndjomou J, Xu H, Oztop I, Matous J, Takemura T, Unutmaz D, Engelman A, Hughes SH, KewalRamani VN. Human immunodeficiency virus type 1 (HIV-1) capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection. J Virol 2012 Apr;86(8):4708-14. doi: 10.1128/JVI.05887-11. Epub 2012 Feb 1. PubMed PMID: 22301145; PubMed Central PMCID: PMC3318671.

The number of TLR9-agonist motifs in the adenovirus genome correlates with induction of DC maturation by adenovirus immune complexes.

/in

Perreau M, Welles HC, Pellaton C, Gjoksi B, Potin L, Martin R, Harari A, Bett A, Casimiro D, Gall J, Barouch DH, Kremer EJ, Pantaleo G. The number of TLR9-agonist motifs in the adenovirus genome correlates with induction of DC maturation by adenovirus immune complexes. J. Virol. 2012; 86:6279-6285.

Correlation of recombinant integrase activity and functional preintegration complex formation during acute infection by replication-defective integrase mutant human immunodeficiency virus.

/in

Li X, Koh Y, Engelman A. Correlation of recombinant integrase activity and functional preintegration complex formation during acute infection by replication-defective integrase mutant human immunodeficiency virus. J Virol 2012 Apr;86(7):3861-79. doi: 10.1128/JVI.06386-11. Epub 2012 Jan 25. PubMed PMID: 22278243; PubMed Central PMCID: PMC3302524.

Impact of anti-orthopoxvirus neutralizing antibodies induced by a heterologous prime-boost HIV-1 vaccine on insert-specific immune responses.

/in ,

Walsh SR, Seaman MS, Grandpre LE, Charbonneau C, Yanosick KE, Metch B, Keefer MC, Dolin R, Baden LR. Impact of anti-orthopoxvirus neutralizing antibodies induced by a heterologous prime-boost HIV-1 vaccine on insert-specific immune responses. Vaccine. 2012 Dec 17;31(1). Epub 2012 Nov 7. PMCID: PMC 3566524.

The road to an effective HIV vaccine.

/in

Baden LR, Dolin R. The road to an effective HIV vaccine. N Engl J Med. 2012 Apr 5;366(14):1343-4. PMID: 22475599 [PubMed – indexed for MEDLINE].

Different pattern of immunoglobulin gene usage by HIV-1 compared to non-HIV-1 antibodies derived from the same infected subject.

/in

Li L, Wang XH, Banerjee S, Volsky B, Williams C, Virland D, Nadas A, Seaman MS, Chen X, Spearman P, Zolla-Pazner S, Gorny MK. Different pattern of immunoglobulin gene usage by HIV-1 compared to non-HIV-1 antibodies derived from the same infected subject. PLoS One. 2012, 7(6): E39534.

In vivo anti-HIV activity of the heparin-activated serine protease inhibitor antithrombin III encapsulated in lymph-targeting immunoliposomes.

/in

Asmal M, Whitney JB, Luedemann C, Carville A, Steen R, Letvin NL, Geiben-Lynn R. In vivo anti-HIV activity of the heparin-activated serine protease inhibitor antithrombin III encapsulated in lymph-targeting immunoliposomes. PLoS One. 2012;7(11):e48234. doi: 10.1371/journal.pone.0048234. Epub 2012 Nov 2. PMID: 23133620; PMCID: PMC3487854.

The structural biology of HIV-1: mechanistic and therapeutic insights.

/in

Engelman A, Cherepanov P. The structural biology of HIV-1: mechanistic and therapeutic insights. Nat Rev Microbiol 2012 Mar 16;10(4):279-90. doi: 10.1038/nrmicro2747. PubMed PMID: 22421880; PubMed Central PMCID: PMC3588166.

Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration.

/in

Koh Y, Wu X, Ferris AL, Matreyek KA, Smith SJ, Lee K, KewalRamani VN, Hughes SH, Engelman A. Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration. J Virol 2013 Jan;87(1):648-58. doi: 10.1128/JVI.01148-12. Epub 2012 Oct 24. PubMed PMID: 23097450; PubMed Central PMCID: PMC3536403.

Increased program cell death-1 expression on T lymphocytes of patients with progressive multifocal leukoencephalopathy.

/in

Tan CS, Bord E, Broge TA Jr, Glotzbecker B, Mills H, Gheuens S, Rosenblatt J, Avigan D, Koralnik IJ. Increased program cell death-1 expression on T lymphocytes of patients with progressive multifocal leukoencephalopathy. J Acquir Immune Defic Syndr. 2012 Jul 1;60(3):244-8. doi: 10.1097/QAI.0b013e31825a313c. PubMed PMID: 22549384; PubMed Central PMCID: PMC3400136.