Distribution and redistribution of HIV-1 nucleocapsid protein in immature, mature, and integrase-inhibited virions: A role for integrase in maturation.

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Fontana J, Jurado KA, Cheng N, Ly NL, Fuchs JR, Gorelick RJ, Engelman AN, Steven AC. Distribution and redistribution of HIV-1 nucleocapsid protein in immature, mature, and integrase-inhibited virions: A role for integrase in maturation. J Virol 2015 Oct; 89(19):9765-80. doi: 10.1128/JVI.01522-15. Epub 2015 Jul 15. PubMed PMID: 26178982; PubMed Central PMCID: PMC4577894.

NK cell exhaustion: bad news for chronic disease?

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Schafer, J.L., Muller-Trutwin, M.C., and Reeves, R.K. 2015. NK cell exhaustion: bad news for chronic disease? Oncotarget. 6(26):21797-21798. PMID: 26392410. PMCID: PMC4673125

A broad range of mutations in HIV-1 neutralizing human monoclonal antibodies specific for V2, V3, and the CD4 binding site.

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Li L, Wang XH, Williams C, Volsky B, Steczko O, Seaman MS, Luthra K, Nyambi P, Nadas A, Giudicelli V, Lefranc MP, Zolla-Pazner S, Gorny MK. A broad range of mutations in HIV-1 neutralizing human monoclonal antibodies specific for V2, V3, and the CD4 binding site. Mol. Immunol. 2015, 66(2):364-74.

Effect of the cytoplasmic domain on antigenic characteristics of HIV-1 envelope glycoprotein.

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Chen J, Kovacs JM, Peng H, Rits-Volloch S, Lu J, Park D, Zablowsky E, Seaman MS, Chen B. HIV-1 ENVELOPE. Effect of the cytoplasmic domain on antigenic characteristics of HIV-1 envelope glycoprotein. Science. 2015, 349(6244):191-5.

Programmed cell death 1 and Helios distinguish TCR-αβ+ double-negative (CD4-CD8-) T cells that derive from self-reactive CD8 T cells.

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Rodríguez-Rodríguez N, Apostolidis SA, Penaloza-MacMaster P, Martín Villa JM, Barouch DH, Tsokos GC, Crispín JC. Programmed cell death 1 and Helios distinguish TCR-αβ+ double-negative (CD4-CD8-) T cells that derive from self-reactive CD8 T cells. J. Immunol. 2015; 194:4207-4214.

A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis.

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Mahan AE, Tedesco J, Dionne K, Baruah K, Cheng HD, De Jager PL, Barouch DH, Suscovich T, Ackerman M, Crispin M, Alter G. A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis. J. Immunol. Methods 2015; 417:34-44.

Embryonic lethality due to arrested cardiac development in Psip1/Hdgfrp2 double-deficient mice.

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Wang H, Shun M-C, Dickson AK, Engelman AN. Embryonic lethality due to arrested cardiac development in Psip1/Hdgfrp2 double-deficient mice. PLoS One 2015; 10:e0137797. doi: 10.1371/journal.pone.0137797. eCollection 2015. PubMed PMID: 26367869; PubMed Central PMCID: PMC4569352.

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys.

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Barouch DH, Alter G, Broge T, Linde C, Ackerman ME, Brown EP, Borducchi EN, Smith KM, Nkolola JP, Liu J, Shields J, Parenteau L, Whitney JB, Abbink P, Ng’ang’a DM, Seaman MS, Lavine CL, Perry JR, Li W, Colantonio AD, Lewis MG, Chen B, Wenschuh H, Reimer U, Piatak M, Lifson JD, Handley SA, Virgin HW, Koutsoukos M, Lorin C, Voss G, Weijtens M, Pau MG, Schuitemaker H. Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys. Science 2015; 349:320-324.

A multivalent clade C HIV-1 Env trimer cocktail elicits a higher magnitude of neutralizing antibodies than any individual component.

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Bricault CA, Kovacs JM, Nkolola JP, Yusim K, Giorgi EE, Shields JL, Perry J, Lavine CL, Cheung A, Ellingson-Strouss K, Rademeyer C, Gray GE, Williamson C, Stamatatos L, Seaman MS, Korber BT, Chen B, Barouch DH. A multivalent clade C HIV-1 Env trimer cocktail elicits a higher magnitude of neutralizing antibodies than any individual component. J. Virol. 2015; 89:2507-2519.

Foreign DNA capture during CRISPR-Cas adaptive immunity.

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Nuñez JK, Harrington LB, Kranzusch PJ, Engelman AN, Doudna JA. Foreign DNA capture during CRISPR-Cas adaptive immunity. Nature 2015 Nov 26; 527(7579):535-8. doi: 10.1038/nature15760. Epub 2015 Oct 21. PubMed PMID: 26503043; PubMed Central PMCID: PMC4662619.